diff --git a/Cargo.lock b/Cargo.lock
index 730cf936c8..dd7c3bd251 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -1454,7 +1454,6 @@ dependencies = [
  "bincode",
  "boxed_error",
  "bytes",
- "cache_control",
  "capacity_builder 0.5.0",
  "chrono",
  "clap",
@@ -1464,7 +1463,6 @@ dependencies = [
  "console_static_text",
  "crossterm",
  "dashmap",
- "data-encoding",
  "deno_ast",
  "deno_bench_util",
  "deno_cache_dir",
@@ -1501,11 +1499,9 @@ dependencies = [
  "flate2",
  "fs3",
  "glibc_version",
- "glob",
  "http 1.1.0",
  "http-body 1.0.0",
  "http-body-util",
- "hyper-util",
  "import_map",
  "indexmap 2.3.0",
  "jsonc-parser",
@@ -1519,7 +1515,6 @@ dependencies = [
  "malva",
  "markup_fmt",
  "memmem",
- "monch",
  "nix",
  "node_resolver",
  "notify",
@@ -1563,15 +1558,12 @@ dependencies = [
  "tracing",
  "tracing-opentelemetry",
  "tracing-subscriber",
- "twox-hash",
  "typed-arena",
  "unicode-width",
  "uuid",
  "walkdir",
- "which",
  "winapi",
  "winres",
- "zeromq",
  "zip",
  "zstd",
 ]
@@ -1657,7 +1649,6 @@ dependencies = [
 name = "deno_cache"
 version = "0.124.0"
 dependencies = [
- "anyhow",
  "async-stream",
  "async-trait",
  "base64 0.21.7",
@@ -1717,12 +1708,9 @@ dependencies = [
  "bytemuck",
  "deno_core",
  "deno_error",
- "deno_terminal 0.2.0",
- "deno_webgpu",
  "image",
  "lcms2",
  "num-traits",
- "serde",
  "thiserror 2.0.3",
 ]
 
@@ -1809,7 +1797,6 @@ checksum = "fe4dccb6147bb3f3ba0c7a48e993bfeb999d2c2e47a81badee80e2b370c8d695"
 name = "deno_cron"
 version = "0.72.0"
 dependencies = [
- "anyhow",
  "async-trait",
  "chrono",
  "deno_core",
@@ -1844,12 +1831,10 @@ dependencies = [
  "rand",
  "ring",
  "rsa",
- "sec1",
  "serde",
  "serde_bytes",
  "sha1",
  "sha2",
- "signature",
  "spki",
  "thiserror 2.0.3",
  "tokio",
@@ -2118,8 +2103,6 @@ dependencies = [
  "http-body-util",
  "log",
  "num-bigint",
- "prost",
- "prost-build",
  "rand",
  "rusqlite",
  "serde",
@@ -2132,7 +2115,6 @@ name = "deno_lib"
 version = "0.8.0"
 dependencies = [
  "capacity_builder 0.5.0",
- "deno_config",
  "deno_error",
  "deno_fs",
  "deno_media_type",
@@ -2154,9 +2136,7 @@ dependencies = [
  "serde",
  "serde_json",
  "sys_traits",
- "test_server",
  "thiserror 2.0.3",
- "tokio",
  "twox-hash",
  "url",
 ]
@@ -2260,7 +2240,6 @@ version = "0.130.0"
 dependencies = [
  "aead-gcm-stream",
  "aes",
- "async-trait",
  "base64 0.21.7",
  "blake2",
  "boxed_error",
@@ -2297,16 +2276,13 @@ dependencies = [
  "hyper 1.6.0",
  "hyper-util",
  "idna",
- "indexmap 2.3.0",
  "ipnetwork",
  "k256",
- "lazy-regex",
  "libc",
  "libsqlite3-sys",
  "libz-sys",
  "md-5",
  "md4",
- "memchr",
  "node_resolver",
  "num-bigint",
  "num-bigint-dig",
@@ -2316,11 +2292,9 @@ dependencies = [
  "p224",
  "p256",
  "p384",
- "path-clean",
  "pbkdf2",
  "pkcs8",
  "rand",
- "regex",
  "ring",
  "ripemd",
  "rsa",
@@ -2332,10 +2306,8 @@ dependencies = [
  "sha2",
  "sha3",
  "signature",
- "simd-json",
  "sm3",
  "spki",
- "stable_deref_trait",
  "sys_traits",
  "thiserror 2.0.3",
  "tokio",
@@ -2586,12 +2558,10 @@ dependencies = [
  "deno_webidl",
  "deno_websocket",
  "deno_webstorage",
- "dlopen2",
  "encoding_rs",
  "fastwebsockets",
  "http 1.1.0",
  "http-body-util",
- "hyper 0.14.28",
  "hyper 1.6.0",
  "hyper-util",
  "libc",
@@ -2601,20 +2571,16 @@ dependencies = [
  "notify",
  "ntapi",
  "once_cell",
- "percent-encoding",
- "regex",
  "rustyline",
  "same-file",
  "serde",
  "sys_traits",
- "tempfile",
  "test_server",
  "thiserror 2.0.3",
  "tokio",
  "tokio-metrics",
  "twox-hash",
  "uuid",
- "which",
  "winapi",
  "windows-sys 0.59.0",
 ]
@@ -2766,7 +2732,6 @@ dependencies = [
  "deno_core",
  "deno_error",
  "deno_webidl",
- "thiserror 2.0.3",
  "urlpattern",
 ]
 
@@ -2847,7 +2812,6 @@ version = "0.187.0"
 dependencies = [
  "deno_core",
  "deno_error",
- "deno_web",
  "rusqlite",
  "thiserror 2.0.3",
 ]
@@ -2954,15 +2918,12 @@ dependencies = [
  "libsui",
  "log",
  "node_resolver",
- "pretty_assertions",
  "serde",
  "serde_json",
  "sys_traits",
  "test_server",
  "thiserror 2.0.3",
  "tokio",
- "tokio-util",
- "twox-hash",
  "url",
 ]
 
diff --git a/cli/Cargo.toml b/cli/Cargo.toml
index dd2b6b79cd..5940ddf9cc 100644
--- a/cli/Cargo.toml
+++ b/cli/Cargo.toml
@@ -98,7 +98,6 @@ base64.workspace = true
 bincode = "=1.3.3"
 boxed_error.workspace = true
 bytes.workspace = true
-cache_control.workspace = true
 capacity_builder.workspace = true
 chrono = { workspace = true, features = ["now"] }
 clap = { version = "=4.5.16", features = ["env", "string", "wrap_help", "error-context"] }
@@ -108,7 +107,6 @@ color-print.workspace = true
 console_static_text.workspace = true
 crossterm = "0.28.1"
 dashmap.workspace = true
-data-encoding.workspace = true
 dhat = { version = "0.3.3", optional = true }
 dissimilar = "=1.0.4"
 dotenvy = "0.15.7"
@@ -121,11 +119,9 @@ faster-hex.workspace = true
 # If you disable the default __vendored_zlib_ng feature above, you _must_ be able to link against `-lz`.
 flate2.workspace = true
 fs3.workspace = true
-glob = "0.3.1"
 http.workspace = true
 http-body.workspace = true
 http-body-util.workspace = true
-hyper-util.workspace = true
 import_map = { version = "=0.21.0", features = ["ext"] }
 indexmap.workspace = true
 jsonc-parser = { workspace = true, features = ["cst", "serde"] }
@@ -138,7 +134,6 @@ lsp-types.workspace = true
 malva = "=0.11.0"
 markup_fmt = "=0.18.0"
 memmem.workspace = true
-monch.workspace = true
 notify.workspace = true
 once_cell.workspace = true
 open = "5.0.1"
@@ -176,13 +171,10 @@ tower-lsp.workspace = true
 tracing = { version = "0.1", features = ["log"], optional = true }
 tracing-opentelemetry = { version = "0.28.0", optional = true }
 tracing-subscriber = { version = "0.3.19", features = ["env-filter"], optional = true }
-twox-hash.workspace = true
 typed-arena = "=2.0.2"
 unicode-width = "0.1.3"
 uuid = { workspace = true, features = ["serde"] }
 walkdir.workspace = true
-which.workspace = true
-zeromq.workspace = true
 zip = { version = "2.1.6", default-features = false, features = ["deflate-flate2"] }
 zstd.workspace = true
 
diff --git a/cli/lib/Cargo.toml b/cli/lib/Cargo.toml
index d0cd59e96d..ba4ce1f4a3 100644
--- a/cli/lib/Cargo.toml
+++ b/cli/lib/Cargo.toml
@@ -15,7 +15,6 @@ path = "lib.rs"
 
 [dependencies]
 capacity_builder.workspace = true
-deno_config = { workspace = true, features = ["sync", "workspace"] }
 deno_error.workspace = true
 deno_fs = { workspace = true, features = ["sync_fs"] }
 deno_media_type.workspace = true
@@ -38,9 +37,5 @@ serde = { workspace = true, features = ["derive"] }
 serde_json.workspace = true
 sys_traits = { workspace = true, features = ["getrandom"] }
 thiserror.workspace = true
-tokio.workspace = true
 twox-hash.workspace = true
 url.workspace = true
-
-[dev-dependencies]
-test_util.workspace = true
diff --git a/cli/rt/Cargo.toml b/cli/rt/Cargo.toml
index 475d051e63..1e66cd2041 100644
--- a/cli/rt/Cargo.toml
+++ b/cli/rt/Cargo.toml
@@ -53,11 +53,8 @@ serde_json.workspace = true
 sys_traits = { workspace = true, features = ["getrandom", "filetime", "libc", "real", "strip_unc", "winapi"] }
 thiserror.workspace = true
 tokio.workspace = true
-tokio-util.workspace = true
-twox-hash.workspace = true
 url.workspace = true
 
 [dev-dependencies]
-pretty_assertions.workspace = true
 sys_traits = { workspace = true, features = ["memory"] }
 test_util.workspace = true
diff --git a/ext/cache/Cargo.toml b/ext/cache/Cargo.toml
index b76d6937e2..bf871ed43e 100644
--- a/ext/cache/Cargo.toml
+++ b/ext/cache/Cargo.toml
@@ -14,7 +14,6 @@ description = "Implementation of Cache API for Deno"
 path = "lib.rs"
 
 [dependencies]
-anyhow.workspace = true
 async-stream.workspace = true
 async-trait.workspace = true
 base64.workspace = true
diff --git a/ext/canvas/Cargo.toml b/ext/canvas/Cargo.toml
index d70877c46b..7aa12ec4e8 100644
--- a/ext/canvas/Cargo.toml
+++ b/ext/canvas/Cargo.toml
@@ -17,8 +17,6 @@ path = "lib.rs"
 bytemuck = "1.17.1"
 deno_core.workspace = true
 deno_error.workspace = true
-deno_terminal.workspace = true
-deno_webgpu.workspace = true
 image = { version = "0.25.4", default-features = false, features = ["png", "jpeg", "bmp", "ico" # NOTE: Temporarily not supported due to build size concerns
   # https://github.com/denoland/deno/pull/25517#issuecomment-2626044644
   # "webp", "gif"
@@ -30,5 +28,4 @@ image = { version = "0.25.4", default-features = false, features = ["png", "jpeg
 # https://github.com/kornelski/rust-lcms2-sys/blob/b8e9c3efcf266b88600318fb519c073b9ebb61b7/README.md#L26
 lcms2 = { version = "6.1.0", features = ["static"] }
 num-traits = { version = "0.2.19" }
-serde = { workspace = true, features = ["derive"] }
 thiserror.workspace = true
diff --git a/ext/cron/Cargo.toml b/ext/cron/Cargo.toml
index 3a4d2b4647..f6a4a6b4bb 100644
--- a/ext/cron/Cargo.toml
+++ b/ext/cron/Cargo.toml
@@ -14,7 +14,6 @@ description = "Implementation of the Deno cron API"
 path = "lib.rs"
 
 [dependencies]
-anyhow.workspace = true
 async-trait.workspace = true
 chrono = { workspace = true, features = ["now"] }
 deno_core.workspace = true
diff --git a/ext/crypto/Cargo.toml b/ext/crypto/Cargo.toml
index 30792821a7..44011ae8dc 100644
--- a/ext/crypto/Cargo.toml
+++ b/ext/crypto/Cargo.toml
@@ -35,12 +35,10 @@ p521 = "0.13.3"
 rand.workspace = true
 ring = { workspace = true, features = ["std"] }
 rsa.workspace = true
-sec1.workspace = true
 serde.workspace = true
 serde_bytes.workspace = true
 sha1.workspace = true
 sha2.workspace = true
-signature.workspace = true
 spki.workspace = true
 thiserror.workspace = true
 tokio.workspace = true
diff --git a/ext/kv/Cargo.toml b/ext/kv/Cargo.toml
index a38b13a31e..46db1f541f 100644
--- a/ext/kv/Cargo.toml
+++ b/ext/kv/Cargo.toml
@@ -34,12 +34,8 @@ http.workspace = true
 http-body-util.workspace = true
 log.workspace = true
 num-bigint.workspace = true
-prost.workspace = true
 rand.workspace = true
 rusqlite.workspace = true
 serde.workspace = true
 thiserror.workspace = true
 url.workspace = true
-
-[build-dependencies]
-prost-build.workspace = true
diff --git a/ext/node/Cargo.toml b/ext/node/Cargo.toml
index 64990d44ce..4c3efe189a 100644
--- a/ext/node/Cargo.toml
+++ b/ext/node/Cargo.toml
@@ -19,7 +19,6 @@ sync_fs = ["deno_fs/sync_fs", "deno_package_json/sync", "node_resolver/sync"]
 [dependencies]
 aead-gcm-stream = "0.4"
 aes.workspace = true
-async-trait.workspace = true
 base64.workspace = true
 blake2 = "0.10.6"
 boxed_error.workspace = true
@@ -55,16 +54,13 @@ http-body-util.workspace = true
 hyper.workspace = true
 hyper-util.workspace = true
 idna = "1.0.3"
-indexmap.workspace = true
 ipnetwork = "0.20.0"
 k256 = "0.13.1"
-lazy-regex.workspace = true
 libc.workspace = true
 libsqlite3-sys = "0.30.1"
 libz-sys.workspace = true
 md-5 = { version = "0.10.5", features = ["oid"] }
 md4 = "0.10.2"
-memchr = "2.7.4"
 node_resolver.workspace = true
 num-bigint.workspace = true
 num-bigint-dig = "0.8.2"
@@ -74,26 +70,22 @@ once_cell.workspace = true
 p224.workspace = true
 p256.workspace = true
 p384.workspace = true
-path-clean = "=0.1.0"
 pbkdf2 = "0.12.1"
 pkcs8 = { version = "0.10.2", features = ["std", "pkcs5", "encryption"] }
 rand.workspace = true
-regex.workspace = true
 ring.workspace = true
 ripemd = { version = "0.1.3", features = ["oid"] }
 rsa.workspace = true
 rusqlite.workspace = true
 scrypt = "0.11.0"
 sec1.workspace = true
-serde = "1.0.149"
+serde.workspace = true
 sha1.workspace = true
 sha2.workspace = true
 sha3 = { version = "0.10.8", features = ["oid"] }
 signature.workspace = true
-simd-json = "0.14.0"
 sm3 = "0.4.2"
 spki.workspace = true
-stable_deref_trait = "1.2.0"
 sys_traits = { workspace = true, features = ["real", "winapi", "libc"] }
 thiserror.workspace = true
 tokio.workspace = true
diff --git a/ext/url/Cargo.toml b/ext/url/Cargo.toml
index 968744723e..998080e9c3 100644
--- a/ext/url/Cargo.toml
+++ b/ext/url/Cargo.toml
@@ -16,7 +16,6 @@ path = "lib.rs"
 [dependencies]
 deno_core.workspace = true
 deno_error.workspace = true
-thiserror.workspace = true
 urlpattern = "0.3.0"
 
 [dev-dependencies]
diff --git a/ext/webstorage/Cargo.toml b/ext/webstorage/Cargo.toml
index ab13f27ac8..477a96c3f6 100644
--- a/ext/webstorage/Cargo.toml
+++ b/ext/webstorage/Cargo.toml
@@ -16,6 +16,5 @@ path = "lib.rs"
 [dependencies]
 deno_core.workspace = true
 deno_error.workspace = true
-deno_web.workspace = true
 rusqlite.workspace = true
 thiserror.workspace = true
diff --git a/runtime/Cargo.toml b/runtime/Cargo.toml
index 2840811534..d0df4fadc6 100644
--- a/runtime/Cargo.toml
+++ b/runtime/Cargo.toml
@@ -78,31 +78,25 @@ deno_webstorage.workspace = true
 node_resolver = { workspace = true, features = ["sync"] }
 
 color-print.workspace = true
-dlopen2.workspace = true
 encoding_rs.workspace = true
 fastwebsockets.workspace = true
 http.workspace = true
 http-body-util.workspace = true
 hyper.workspace = true
 hyper-util.workspace = true
-hyper_v014 = { workspace = true, features = ["server", "stream", "http1", "http2", "runtime"] }
 libc.workspace = true
 log.workspace = true
 notify.workspace = true
 once_cell.workspace = true
-percent-encoding.workspace = true
-regex.workspace = true
 rustyline = { workspace = true, features = ["custom-bindings"] }
 same-file = "1.0.6"
 serde.workspace = true
 sys_traits.workspace = true
-tempfile.workspace = true
 thiserror.workspace = true
 tokio.workspace = true
 tokio-metrics.workspace = true
 twox-hash.workspace = true
 uuid.workspace = true
-which.workspace = true
 
 [target.'cfg(windows)'.dependencies]
 winapi = { workspace = true, features = ["commapi", "knownfolders", "mswsock", "objbase", "psapi", "shlobj", "tlhelp32", "winbase", "winerror", "winuser", "winsock2"] }