diff --git a/crates/ruff_linter/resources/test/fixtures/flake8_commas/COM81.py b/crates/ruff_linter/resources/test/fixtures/flake8_commas/COM81.py
index 8c8e368dba..9941fa63cd 100644
--- a/crates/ruff_linter/resources/test/fixtures/flake8_commas/COM81.py
+++ b/crates/ruff_linter/resources/test/fixtures/flake8_commas/COM81.py
@@ -663,4 +663,15 @@ class C[
 
 type X[T,] = T
 def f[T,](): pass
-class C[T,]: pass
\ No newline at end of file
+class C[T,]: pass
+
+# t-string examples
+kwargs.pop("remove", t"this {trailing_comma}",)
+kwargs.pop("remove", t"this {f"{trailing_comma}"}",)
+
+t"""This is a test. {
+    "Another sentence."
+    if True else
+    "Don't add a trailing comma here ->"
+}"""
+
diff --git a/crates/ruff_linter/resources/test/fixtures/flake8_implicit_str_concat/ISC.py b/crates/ruff_linter/resources/test/fixtures/flake8_implicit_str_concat/ISC.py
index 09fba4a9db..a26864e35e 100644
--- a/crates/ruff_linter/resources/test/fixtures/flake8_implicit_str_concat/ISC.py
+++ b/crates/ruff_linter/resources/test/fixtures/flake8_implicit_str_concat/ISC.py
@@ -187,3 +187,24 @@ _ = (
 		# leading comment
     "end"
 )
+
+# https://github.com/astral-sh/ruff/issues/20310
+# ISC001
+t"The quick " t"brown fox."
+
+# ISC002
+t"The quick brown fox jumps over the lazy "\
+t"dog."
+
+# ISC003
+(
+    t"The quick brown fox jumps over the lazy "
+    + t"dog"
+)
+
+# nested examples with both t and f-strings
+_ = "a" f"b {t"c" t"d"} e" "f"
+_ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+_ = f"b {t"abc" \
+    t"def"} g"
+
diff --git a/crates/ruff_linter/src/directives.rs b/crates/ruff_linter/src/directives.rs
index bded1a8f2b..a642d57271 100644
--- a/crates/ruff_linter/src/directives.rs
+++ b/crates/ruff_linter/src/directives.rs
@@ -125,26 +125,27 @@ fn extract_noqa_line_for(tokens: &Tokens, locator: &Locator, indexer: &Indexer)
     }
 
     // The capacity allocated here might be more than we need if there are
-    // nested f-strings.
-    let mut fstring_mappings = Vec::with_capacity(indexer.fstring_ranges().len());
+    // nested interpolated strings.
+    let mut interpolated_string_mappings =
+        Vec::with_capacity(indexer.interpolated_string_ranges().len());
 
-    // For nested f-strings, we expect `noqa` directives on the last line of the
-    // outermost f-string. The last f-string range will be used to skip over
-    // the inner f-strings.
-    let mut last_fstring_range: TextRange = TextRange::default();
-    for fstring_range in indexer.fstring_ranges().values() {
-        if !locator.contains_line_break(*fstring_range) {
+    // For nested interpolated strings, we expect `noqa` directives on the last line of the
+    // outermost interpolated string. The last interpolated string range will be used to skip over
+    // the inner interpolated strings.
+    let mut last_interpolated_string_range: TextRange = TextRange::default();
+    for interpolated_string_range in indexer.interpolated_string_ranges().values() {
+        if !locator.contains_line_break(*interpolated_string_range) {
             continue;
         }
-        if last_fstring_range.contains_range(*fstring_range) {
+        if last_interpolated_string_range.contains_range(*interpolated_string_range) {
             continue;
         }
         let new_range = TextRange::new(
-            locator.line_start(fstring_range.start()),
-            fstring_range.end(),
+            locator.line_start(interpolated_string_range.start()),
+            interpolated_string_range.end(),
         );
-        fstring_mappings.push(new_range);
-        last_fstring_range = new_range;
+        interpolated_string_mappings.push(new_range);
+        last_interpolated_string_range = new_range;
     }
 
     let mut continuation_mappings = Vec::new();
@@ -172,11 +173,11 @@ fn extract_noqa_line_for(tokens: &Tokens, locator: &Locator, indexer: &Indexer)
 
     // Merge the mappings in sorted order
     let mut mappings = NoqaMapping::with_capacity(
-        continuation_mappings.len() + string_mappings.len() + fstring_mappings.len(),
+        continuation_mappings.len() + string_mappings.len() + interpolated_string_mappings.len(),
     );
 
     let string_mappings = SortedMergeIter {
-        left: fstring_mappings.into_iter().peekable(),
+        left: interpolated_string_mappings.into_iter().peekable(),
         right: string_mappings.into_iter().peekable(),
     };
     let all_mappings = SortedMergeIter {
@@ -497,12 +498,35 @@ end'''
             NoqaMapping::from_iter([TextRange::new(TextSize::from(6), TextSize::from(70))])
         );
 
+        let contents = "x = 1
+y = t'''abc
+def {f'''nested
+interpolated string''' f'another nested'}
+end'''
+";
+        assert_eq!(
+            noqa_mappings(contents),
+            NoqaMapping::from_iter([TextRange::new(TextSize::from(6), TextSize::from(82))])
+        );
+
         let contents = "x = 1
 y = f'normal'
 z = f'another but {f'nested but {f'still single line'} nested'}'
 ";
         assert_eq!(noqa_mappings(contents), NoqaMapping::default());
 
+        let contents = "x = 1
+y = t'normal'
+z = t'another but {t'nested but {t'still single line'} nested'}'
+";
+        assert_eq!(noqa_mappings(contents), NoqaMapping::default());
+
+        let contents = "x = 1
+y = f'normal'
+z = f'another but {t'nested but {f'still single line'} nested'}'
+";
+        assert_eq!(noqa_mappings(contents), NoqaMapping::default());
+
         let contents = r"x = \
     1";
         assert_eq!(
diff --git a/crates/ruff_linter/src/fix/edits.rs b/crates/ruff_linter/src/fix/edits.rs
index e4ac1b5d0f..05e90519eb 100644
--- a/crates/ruff_linter/src/fix/edits.rs
+++ b/crates/ruff_linter/src/fix/edits.rs
@@ -370,8 +370,8 @@ pub(crate) fn adjust_indentation(
 
     // If the range includes a multi-line string, use LibCST to ensure that we don't adjust the
     // whitespace _within_ the string.
-    let contains_multiline_string =
-        indexer.multiline_ranges().intersects(range) || indexer.fstring_ranges().intersects(range);
+    let contains_multiline_string = indexer.multiline_ranges().intersects(range)
+        || indexer.interpolated_string_ranges().intersects(range);
 
     // If the range has mixed indentation, we will use LibCST as well.
     let mixed_indentation = contents.universal_newlines().any(|line| {
diff --git a/crates/ruff_linter/src/rules/flake8_commas/rules/trailing_commas.rs b/crates/ruff_linter/src/rules/flake8_commas/rules/trailing_commas.rs
index e759f493b2..71c422de68 100644
--- a/crates/ruff_linter/src/rules/flake8_commas/rules/trailing_commas.rs
+++ b/crates/ruff_linter/src/rules/flake8_commas/rules/trailing_commas.rs
@@ -250,23 +250,23 @@ pub(crate) fn trailing_commas(
     locator: &Locator,
     indexer: &Indexer,
 ) {
-    let mut fstrings = 0u32;
+    let mut interpolated_strings = 0u32;
     let simple_tokens = tokens.iter().filter_map(|token| {
         match token.kind() {
             // Completely ignore comments -- they just interfere with the logic.
             TokenKind::Comment => None,
-            // F-strings are handled as `String` token type with the complete range
-            // of the outermost f-string. This means that the expression inside the
-            // f-string is not checked for trailing commas.
-            TokenKind::FStringStart => {
-                fstrings = fstrings.saturating_add(1);
+            // F-strings and t-strings are handled as `String` token type with the complete range
+            // of the outermost interpolated string. This means that the expression inside the
+            // interpolated string is not checked for trailing commas.
+            TokenKind::FStringStart | TokenKind::TStringStart => {
+                interpolated_strings = interpolated_strings.saturating_add(1);
                 None
             }
-            TokenKind::FStringEnd => {
-                fstrings = fstrings.saturating_sub(1);
-                if fstrings == 0 {
+            TokenKind::FStringEnd | TokenKind::TStringEnd => {
+                interpolated_strings = interpolated_strings.saturating_sub(1);
+                if interpolated_strings == 0 {
                     indexer
-                        .fstring_ranges()
+                        .interpolated_string_ranges()
                         .outermost(token.start())
                         .map(|range| SimpleToken::new(TokenType::String, range))
                 } else {
@@ -274,7 +274,7 @@ pub(crate) fn trailing_commas(
                 }
             }
             _ => {
-                if fstrings == 0 {
+                if interpolated_strings == 0 {
                     Some(SimpleToken::from(token.as_tuple()))
                 } else {
                     None
diff --git a/crates/ruff_linter/src/rules/flake8_commas/snapshots/ruff_linter__rules__flake8_commas__tests__COM81.py.snap b/crates/ruff_linter/src/rules/flake8_commas/snapshots/ruff_linter__rules__flake8_commas__tests__COM81.py.snap
index 8dbe00d72d..cc315df9bb 100644
--- a/crates/ruff_linter/src/rules/flake8_commas/snapshots/ruff_linter__rules__flake8_commas__tests__COM81.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_commas/snapshots/ruff_linter__rules__flake8_commas__tests__COM81.py.snap
@@ -1016,6 +1016,7 @@ help: Remove trailing comma
 664 + type X[T] = T
 665 | def f[T,](): pass
 666 | class C[T,]: pass
+667 | 
 
 COM819 [*] Trailing comma prohibited
    --> COM81.py:665:8
@@ -1032,6 +1033,8 @@ help: Remove trailing comma
     - def f[T,](): pass
 665 + def f[T](): pass
 666 | class C[T,]: pass
+667 | 
+668 | # t-string examples
 
 COM819 [*] Trailing comma prohibited
    --> COM81.py:666:10
@@ -1040,6 +1043,8 @@ COM819 [*] Trailing comma prohibited
 665 | def f[T,](): pass
 666 | class C[T,]: pass
     |          ^
+667 |
+668 | # t-string examples
     |
 help: Remove trailing comma
 663 | 
@@ -1047,3 +1052,44 @@ help: Remove trailing comma
 665 | def f[T,](): pass
     - class C[T,]: pass
 666 + class C[T]: pass
+667 | 
+668 | # t-string examples
+669 | kwargs.pop("remove", t"this {trailing_comma}",)
+
+COM819 [*] Trailing comma prohibited
+   --> COM81.py:669:46
+    |
+668 | # t-string examples
+669 | kwargs.pop("remove", t"this {trailing_comma}",)
+    |                                              ^
+670 | kwargs.pop("remove", t"this {f"{trailing_comma}"}",)
+    |
+help: Remove trailing comma
+666 | class C[T,]: pass
+667 | 
+668 | # t-string examples
+    - kwargs.pop("remove", t"this {trailing_comma}",)
+669 + kwargs.pop("remove", t"this {trailing_comma}")
+670 | kwargs.pop("remove", t"this {f"{trailing_comma}"}",)
+671 | 
+672 | t"""This is a test. {
+
+COM819 [*] Trailing comma prohibited
+   --> COM81.py:670:51
+    |
+668 | # t-string examples
+669 | kwargs.pop("remove", t"this {trailing_comma}",)
+670 | kwargs.pop("remove", t"this {f"{trailing_comma}"}",)
+    |                                                   ^
+671 |
+672 | t"""This is a test. {
+    |
+help: Remove trailing comma
+667 | 
+668 | # t-string examples
+669 | kwargs.pop("remove", t"this {trailing_comma}",)
+    - kwargs.pop("remove", t"this {f"{trailing_comma}"}",)
+670 + kwargs.pop("remove", t"this {f"{trailing_comma}"}")
+671 | 
+672 | t"""This is a test. {
+673 |     "Another sentence."
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/explicit.rs b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/explicit.rs
index ba2a9f61a0..7a6e33aebc 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/explicit.rs
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/explicit.rs
@@ -74,6 +74,7 @@ pub(crate) fn explicit(checker: &Checker, expr: &Expr) {
                     Expr::StringLiteral(_) | Expr::FString(_),
                     Expr::StringLiteral(_) | Expr::FString(_)
                 ) | (Expr::BytesLiteral(_), Expr::BytesLiteral(_))
+                    | (Expr::TString(_), Expr::TString(_))
             );
             if concatable
                 && checker
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/implicit.rs b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/implicit.rs
index b7db8fcdfe..7961f22b6e 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/implicit.rs
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/rules/implicit.rs
@@ -123,21 +123,32 @@ pub(crate) fn implicit(
         let (a_range, b_range) = match (a_token.kind(), b_token.kind()) {
             (TokenKind::String, TokenKind::String) => (a_token.range(), b_token.range()),
             (TokenKind::String, TokenKind::FStringStart) => {
-                match indexer.fstring_ranges().innermost(b_token.start()) {
+                match indexer
+                    .interpolated_string_ranges()
+                    .innermost(b_token.start())
+                {
                     Some(b_range) => (a_token.range(), b_range),
                     None => continue,
                 }
             }
             (TokenKind::FStringEnd, TokenKind::String) => {
-                match indexer.fstring_ranges().innermost(a_token.start()) {
+                match indexer
+                    .interpolated_string_ranges()
+                    .innermost(a_token.start())
+                {
                     Some(a_range) => (a_range, b_token.range()),
                     None => continue,
                 }
             }
-            (TokenKind::FStringEnd, TokenKind::FStringStart) => {
+            (TokenKind::FStringEnd, TokenKind::FStringStart)
+            | (TokenKind::TStringEnd, TokenKind::TStringStart) => {
                 match (
-                    indexer.fstring_ranges().innermost(a_token.start()),
-                    indexer.fstring_ranges().innermost(b_token.start()),
+                    indexer
+                        .interpolated_string_ranges()
+                        .innermost(a_token.start()),
+                    indexer
+                        .interpolated_string_ranges()
+                        .innermost(b_token.start()),
                 ) {
                     (Some(a_range), Some(b_range)) => (a_range, b_range),
                     _ => continue,
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC001_ISC.py.snap b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC001_ISC.py.snap
index f232df6352..b416434247 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC001_ISC.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC001_ISC.py.snap
@@ -484,3 +484,104 @@ help: Combine string literals
 94 | 
 95 | 
 96 | # Mixed literal + non-literal scenarios
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:193:1
+    |
+191 | # https://github.com/astral-sh/ruff/issues/20310
+192 | # ISC001
+193 | t"The quick " t"brown fox."
+    | ^^^^^^^^^^^^^^^^^^^^^^^^^^^
+194 |
+195 | # ISC002
+    |
+help: Combine string literals
+190 | 
+191 | # https://github.com/astral-sh/ruff/issues/20310
+192 | # ISC001
+    - t"The quick " t"brown fox."
+193 + t"The quick brown fox."
+194 | 
+195 | # ISC002
+196 | t"The quick brown fox jumps over the lazy "\
+
+ISC001 Implicitly concatenated string literals on one line
+   --> ISC.py:206:5
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |     ^^^^^^^^^^^^^^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+
+ISC001 Implicitly concatenated string literals on one line
+   --> ISC.py:206:9
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |         ^^^^^^^^^^^^^^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:206:14
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |              ^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+203 | )
+204 | 
+205 | # nested examples with both t and f-strings
+    - _ = "a" f"b {t"c" t"d"} e" "f"
+206 + _ = "a" f"b {t"cd"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:207:10
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+    |          ^^^^^^^^^^^^^^^^^^^^^^^
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+    |
+help: Combine string literals
+204 | 
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    - _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+207 + _ = t"b {f"cd {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+210 | 
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:207:20
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+    |                    ^^^^^^^^^
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+    |
+help: Combine string literals
+204 | 
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    - _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+207 + _ = t"b {f"c" f"d {t"ef"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+210 |
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC002_ISC.py.snap b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC002_ISC.py.snap
index fc84adef37..290691d0a7 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC002_ISC.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC002_ISC.py.snap
@@ -26,3 +26,25 @@ ISC002 Implicitly concatenated string literals over multiple lines
 76 |
 77 |   # Explicitly concatenated nested f-strings
    |
+
+ISC002 Implicitly concatenated string literals over multiple lines
+   --> ISC.py:196:1
+    |
+195 |   # ISC002
+196 | / t"The quick brown fox jumps over the lazy "\
+197 | | t"dog."
+    | |_______^
+198 |
+199 |   # ISC003
+    |
+
+ISC002 Implicitly concatenated string literals over multiple lines
+   --> ISC.py:208:10
+    |
+206 |   _ = "a" f"b {t"c" t"d"} e" "f"
+207 |   _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 |   _ = f"b {t"abc" \
+    |  __________^
+209 | |     t"def"} g"
+    | |__________^
+    |
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC003_ISC.py.snap b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC003_ISC.py.snap
index b990f5e41b..7e142fef36 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC003_ISC.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__ISC003_ISC.py.snap
@@ -337,3 +337,23 @@ help: Remove redundant '+' operator to implicitly concatenate
 187 | 		# leading comment
 188 |     "end"
 189 | )
+
+ISC003 [*] Explicitly concatenated string should be implicitly concatenated
+   --> ISC.py:201:5
+    |
+199 |   # ISC003
+200 |   (
+201 | /     t"The quick brown fox jumps over the lazy "
+202 | |     + t"dog"
+    | |____________^
+203 |   )
+    |
+help: Remove redundant '+' operator to implicitly concatenate
+199 | # ISC003
+200 | (
+201 |     t"The quick brown fox jumps over the lazy "
+    -     + t"dog"
+202 +      t"dog"
+203 | )
+204 | 
+205 | # nested examples with both t and f-strings
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC001_ISC.py.snap b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC001_ISC.py.snap
index f232df6352..b416434247 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC001_ISC.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC001_ISC.py.snap
@@ -484,3 +484,104 @@ help: Combine string literals
 94 | 
 95 | 
 96 | # Mixed literal + non-literal scenarios
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:193:1
+    |
+191 | # https://github.com/astral-sh/ruff/issues/20310
+192 | # ISC001
+193 | t"The quick " t"brown fox."
+    | ^^^^^^^^^^^^^^^^^^^^^^^^^^^
+194 |
+195 | # ISC002
+    |
+help: Combine string literals
+190 | 
+191 | # https://github.com/astral-sh/ruff/issues/20310
+192 | # ISC001
+    - t"The quick " t"brown fox."
+193 + t"The quick brown fox."
+194 | 
+195 | # ISC002
+196 | t"The quick brown fox jumps over the lazy "\
+
+ISC001 Implicitly concatenated string literals on one line
+   --> ISC.py:206:5
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |     ^^^^^^^^^^^^^^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+
+ISC001 Implicitly concatenated string literals on one line
+   --> ISC.py:206:9
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |         ^^^^^^^^^^^^^^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:206:14
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    |              ^^^^^^^^^
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+    |
+help: Combine string literals
+203 | )
+204 | 
+205 | # nested examples with both t and f-strings
+    - _ = "a" f"b {t"c" t"d"} e" "f"
+206 + _ = "a" f"b {t"cd"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:207:10
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+    |          ^^^^^^^^^^^^^^^^^^^^^^^
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+    |
+help: Combine string literals
+204 | 
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    - _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+207 + _ = t"b {f"cd {t"e" t"f"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+210 | 
+
+ISC001 [*] Implicitly concatenated string literals on one line
+   --> ISC.py:207:20
+    |
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+207 | _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+    |                    ^^^^^^^^^
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+    |
+help: Combine string literals
+204 | 
+205 | # nested examples with both t and f-strings
+206 | _ = "a" f"b {t"c" t"d"} e" "f"
+    - _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+207 + _ = t"b {f"c" f"d {t"ef"} g"} h"
+208 | _ = f"b {t"abc" \
+209 |     t"def"} g"
+210 |
diff --git a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC002_ISC.py.snap b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC002_ISC.py.snap
index c0a1f8995f..30b777f4e0 100644
--- a/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC002_ISC.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_implicit_str_concat/snapshots/ruff_linter__rules__flake8_implicit_str_concat__tests__multiline_ISC002_ISC.py.snap
@@ -67,3 +67,25 @@ ISC002 Implicitly concatenated string literals over multiple lines
 76 |
 77 |   # Explicitly concatenated nested f-strings
    |
+
+ISC002 Implicitly concatenated string literals over multiple lines
+   --> ISC.py:196:1
+    |
+195 |   # ISC002
+196 | / t"The quick brown fox jumps over the lazy "\
+197 | | t"dog."
+    | |_______^
+198 |
+199 |   # ISC003
+    |
+
+ISC002 Implicitly concatenated string literals over multiple lines
+   --> ISC.py:208:10
+    |
+206 |   _ = "a" f"b {t"c" t"d"} e" "f"
+207 |   _ = t"b {f"c" f"d {t"e" t"f"} g"} h"
+208 |   _ = f"b {t"abc" \
+    |  __________^
+209 | |     t"def"} g"
+    | |__________^
+    |
diff --git a/crates/ruff_linter/src/rules/pycodestyle/snapshots/ruff_linter__rules__pycodestyle__tests__W605_W605_1.py.snap b/crates/ruff_linter/src/rules/pycodestyle/snapshots/ruff_linter__rules__pycodestyle__tests__W605_W605_1.py.snap
index 9a61dced69..4efee366a1 100644
--- a/crates/ruff_linter/src/rules/pycodestyle/snapshots/ruff_linter__rules__pycodestyle__tests__W605_W605_1.py.snap
+++ b/crates/ruff_linter/src/rules/pycodestyle/snapshots/ruff_linter__rules__pycodestyle__tests__W605_W605_1.py.snap
@@ -402,25 +402,6 @@ help: Add backslash to escape sequence
 96 | 
 97 | #: Okay
 
-W605 [*] Invalid escape sequence: `\w`
-   --> W605_1.py:109:1
-    |
-107 | regex = t'\w'  # noqa
-108 | regex = t'''
-109 | \w
-    | ^^
-110 | '''  # noqa
-    |
-help: Use a raw string literal
-105 | '''
-106 | s = t'\\'
-107 | regex = t'\w'  # noqa
-    - regex = t'''
-108 + regex = rt'''
-109 | \w
-110 | '''  # noqa
-111 | 
-
 W605 [*] Invalid escape sequence: `\_`
    --> W605_1.py:112:13
     |
diff --git a/crates/ruff_python_ast/src/str.rs b/crates/ruff_python_ast/src/str.rs
index a9096a5218..a058cf4c8e 100644
--- a/crates/ruff_python_ast/src/str.rs
+++ b/crates/ruff_python_ast/src/str.rs
@@ -210,6 +210,58 @@ pub const SINGLE_QUOTE_BYTE_PREFIXES: &[&str] = &[
     "b'",
 ];
 
+/// Includes all permutations of `t` and `rt`. This includes all possible orders, and all possible
+/// casings, for both single and triple quotes.
+///
+/// See: <https://docs.python.org/3/reference/lexical_analysis.html#string-and-bytes-literals>
+#[rustfmt::skip]
+pub const TRIPLE_QUOTE_TEMPLATE_PREFIXES: &[&str] = &[
+    "TR\"\"\"",
+    "Tr\"\"\"",
+    "tR\"\"\"",
+    "tr\"\"\"",
+    "RT\"\"\"",
+    "Rt\"\"\"",
+    "rT\"\"\"",
+    "rt\"\"\"",
+    "TR'''",
+    "Tr'''",
+    "tR'''",
+    "tr'''",
+    "RT'''",
+    "Rt'''",
+    "rT'''",
+    "rt'''",
+    "T\"\"\"",
+    "t\"\"\"",
+    "T'''",
+    "t'''",
+];
+
+#[rustfmt::skip]
+pub const SINGLE_QUOTE_TEMPLATE_PREFIXES: &[&str] = &[
+    "TR\"",
+    "Tr\"",
+    "tR\"",
+    "tr\"",
+    "RT\"",
+    "Rt\"",
+    "rT\"",
+    "rt\"",
+    "TR'",
+    "Tr'",
+    "tR'",
+    "tr'",
+    "RT'",
+    "Rt'",
+    "rT'",
+    "rt'",
+    "T\"",
+    "t\"",
+    "T'",
+    "t'",
+];
+
 /// Strip the leading and trailing quotes from a string.
 /// Assumes that the string is a valid string literal, but does not verify that the string
 /// is a "simple" string literal (i.e., that it does not contain any implicit concatenations).
@@ -229,7 +281,7 @@ pub fn raw_contents_range(contents: &str) -> Option<TextRange> {
     ))
 }
 
-/// An [`AhoCorasick`] matcher for string and byte literal prefixes.
+/// An [`AhoCorasick`] matcher for string, template, and bytes literal prefixes.
 static PREFIX_MATCHER: LazyLock<AhoCorasick> = LazyLock::new(|| {
     AhoCorasick::builder()
         .start_kind(StartKind::Anchored)
@@ -239,19 +291,21 @@ static PREFIX_MATCHER: LazyLock<AhoCorasick> = LazyLock::new(|| {
             TRIPLE_QUOTE_STR_PREFIXES
                 .iter()
                 .chain(TRIPLE_QUOTE_BYTE_PREFIXES)
+                .chain(TRIPLE_QUOTE_TEMPLATE_PREFIXES)
                 .chain(SINGLE_QUOTE_STR_PREFIXES)
-                .chain(SINGLE_QUOTE_BYTE_PREFIXES),
+                .chain(SINGLE_QUOTE_BYTE_PREFIXES)
+                .chain(SINGLE_QUOTE_TEMPLATE_PREFIXES),
         )
         .unwrap()
 });
 
-/// Return the leading quote for a string or byte literal (e.g., `"""`).
+/// Return the leading quote for a string, template, or bytes literal (e.g., `"""`).
 pub fn leading_quote(content: &str) -> Option<&str> {
     let mat = PREFIX_MATCHER.find(Input::new(content).anchored(Anchored::Yes))?;
     Some(&content[mat.start()..mat.end()])
 }
 
-/// Return the trailing quote string for a string or byte literal (e.g., `"""`).
+/// Return the trailing quote string for a string, template, or bytes literal (e.g., `"""`).
 pub fn trailing_quote(content: &str) -> Option<&str> {
     if content.ends_with("'''") {
         Some("'''")
@@ -268,14 +322,16 @@ pub fn trailing_quote(content: &str) -> Option<&str> {
 
 /// Return `true` if the string is a triple-quote string or byte prefix.
 pub fn is_triple_quote(content: &str) -> bool {
-    TRIPLE_QUOTE_STR_PREFIXES.contains(&content) || TRIPLE_QUOTE_BYTE_PREFIXES.contains(&content)
+    TRIPLE_QUOTE_STR_PREFIXES.contains(&content)
+        || TRIPLE_QUOTE_BYTE_PREFIXES.contains(&content)
+        || TRIPLE_QUOTE_TEMPLATE_PREFIXES.contains(&content)
 }
 
 #[cfg(test)]
 mod tests {
     use super::{
-        SINGLE_QUOTE_BYTE_PREFIXES, SINGLE_QUOTE_STR_PREFIXES, TRIPLE_QUOTE_BYTE_PREFIXES,
-        TRIPLE_QUOTE_STR_PREFIXES,
+        SINGLE_QUOTE_BYTE_PREFIXES, SINGLE_QUOTE_STR_PREFIXES, SINGLE_QUOTE_TEMPLATE_PREFIXES,
+        TRIPLE_QUOTE_BYTE_PREFIXES, TRIPLE_QUOTE_STR_PREFIXES, TRIPLE_QUOTE_TEMPLATE_PREFIXES,
     };
 
     #[test]
@@ -283,8 +339,10 @@ mod tests {
         let prefixes = TRIPLE_QUOTE_STR_PREFIXES
             .iter()
             .chain(TRIPLE_QUOTE_BYTE_PREFIXES)
+            .chain(TRIPLE_QUOTE_TEMPLATE_PREFIXES)
             .chain(SINGLE_QUOTE_STR_PREFIXES)
             .chain(SINGLE_QUOTE_BYTE_PREFIXES)
+            .chain(SINGLE_QUOTE_TEMPLATE_PREFIXES)
             .collect::<Vec<_>>();
         for (i, prefix_i) in prefixes.iter().enumerate() {
             for (j, prefix_j) in prefixes.iter().enumerate() {
diff --git a/crates/ruff_python_index/src/indexer.rs b/crates/ruff_python_index/src/indexer.rs
index 82f913f484..04c44a7c4b 100644
--- a/crates/ruff_python_index/src/indexer.rs
+++ b/crates/ruff_python_index/src/indexer.rs
@@ -9,15 +9,17 @@ use ruff_python_trivia::{
 use ruff_source_file::LineRanges;
 use ruff_text_size::{Ranged, TextRange, TextSize};
 
-use crate::fstring_ranges::{FStringRanges, FStringRangesBuilder};
+use crate::interpolated_string_ranges::{
+    InterpolatedStringRanges, InterpolatedStringRangesBuilder,
+};
 use crate::multiline_ranges::{MultilineRanges, MultilineRangesBuilder};
 
 pub struct Indexer {
     /// Stores the start offset of continuation lines.
     continuation_lines: Vec<TextSize>,
 
-    /// The range of all f-string in the source document.
-    fstring_ranges: FStringRanges,
+    /// The range of all interpolated strings in the source document.
+    interpolated_string_ranges: InterpolatedStringRanges,
 
     /// The range of all multiline strings in the source document.
     multiline_ranges: MultilineRanges,
@@ -30,7 +32,7 @@ impl Indexer {
     pub fn from_tokens(tokens: &Tokens, source: &str) -> Self {
         assert!(TextSize::try_from(source.len()).is_ok());
 
-        let mut fstring_ranges_builder = FStringRangesBuilder::default();
+        let mut interpolated_string_ranges_builder = InterpolatedStringRangesBuilder::default();
         let mut multiline_ranges_builder = MultilineRangesBuilder::default();
         let mut continuation_lines = Vec::new();
         let mut comment_ranges = Vec::new();
@@ -59,7 +61,7 @@ impl Indexer {
                 }
             }
 
-            fstring_ranges_builder.visit_token(token);
+            interpolated_string_ranges_builder.visit_token(token);
             multiline_ranges_builder.visit_token(token);
 
             match token.kind() {
@@ -82,7 +84,7 @@ impl Indexer {
 
         Self {
             continuation_lines,
-            fstring_ranges: fstring_ranges_builder.finish(),
+            interpolated_string_ranges: interpolated_string_ranges_builder.finish(),
             multiline_ranges: multiline_ranges_builder.finish(),
             comment_ranges: CommentRanges::new(comment_ranges),
         }
@@ -93,9 +95,9 @@ impl Indexer {
         &self.comment_ranges
     }
 
-    /// Returns the byte offset ranges of f-strings.
-    pub const fn fstring_ranges(&self) -> &FStringRanges {
-        &self.fstring_ranges
+    /// Returns the byte offset ranges of interpolated strings.
+    pub const fn interpolated_string_ranges(&self) -> &InterpolatedStringRanges {
+        &self.interpolated_string_ranges
     }
 
     /// Returns the byte offset ranges of multiline strings.
@@ -356,7 +358,7 @@ f"implicit " f"concatenation"
         .trim();
         assert_eq!(
             new_indexer(contents)
-                .fstring_ranges()
+                .interpolated_string_ranges()
                 .values()
                 .copied()
                 .collect::<Vec<_>>(),
@@ -390,7 +392,7 @@ f-string"""}
         .trim();
         assert_eq!(
             new_indexer(contents)
-                .fstring_ranges()
+                .interpolated_string_ranges()
                 .values()
                 .copied()
                 .collect::<Vec<_>>(),
@@ -504,11 +506,17 @@ the end"""
             ),
         ] {
             assert_eq!(
-                indexer.fstring_ranges().innermost(offset).unwrap(),
+                indexer
+                    .interpolated_string_ranges()
+                    .innermost(offset)
+                    .unwrap(),
                 innermost_range
             );
             assert_eq!(
-                indexer.fstring_ranges().outermost(offset).unwrap(),
+                indexer
+                    .interpolated_string_ranges()
+                    .outermost(offset)
+                    .unwrap(),
                 outermost_range
             );
         }
diff --git a/crates/ruff_python_index/src/fstring_ranges.rs b/crates/ruff_python_index/src/interpolated_string_ranges.rs
similarity index 70%
rename from crates/ruff_python_index/src/fstring_ranges.rs
rename to crates/ruff_python_index/src/interpolated_string_ranges.rs
index 089050334e..45dc7c2765 100644
--- a/crates/ruff_python_index/src/fstring_ranges.rs
+++ b/crates/ruff_python_index/src/interpolated_string_ranges.rs
@@ -3,17 +3,17 @@ use std::collections::BTreeMap;
 use ruff_python_parser::{Token, TokenKind};
 use ruff_text_size::{Ranged, TextRange, TextSize};
 
-/// Stores the ranges of all f-strings in a file sorted by [`TextRange::start`].
-/// There can be multiple overlapping ranges for nested f-strings.
+/// Stores the ranges of all interpolated strings in a file sorted by [`TextRange::start`].
+/// There can be multiple overlapping ranges for nested interpolated strings.
 ///
-/// Note that the ranges for all unterminated f-strings are not stored.
+/// Note that the ranges for all unterminated interpolated strings are not stored.
 #[derive(Debug)]
-pub struct FStringRanges {
-    // Mapping from the f-string start location to its range.
+pub struct InterpolatedStringRanges {
+    // Mapping from the interpolated string start location to its range.
     raw: BTreeMap<TextSize, TextRange>,
 }
 
-impl FStringRanges {
+impl InterpolatedStringRanges {
     /// Returns `true` if the given range intersects with any f-string range.
     pub fn intersects(&self, target: TextRange) -> bool {
         self.raw
@@ -61,17 +61,17 @@ impl FStringRanges {
             .map(|(_, range)| *range)
     }
 
-    /// Returns an iterator over all f-string [`TextRange`] sorted by their
+    /// Returns an iterator over all interpolated string [`TextRange`] sorted by their
     /// start location.
     ///
-    /// For nested f-strings, the outermost f-string is yielded first, moving
+    /// For nested interpolated strings, the outermost interpolated string is yielded first, moving
     /// inwards with each iteration.
     #[inline]
     pub fn values(&self) -> impl Iterator<Item = &TextRange> + '_ {
         self.raw.values()
     }
 
-    /// Returns the number of f-string ranges stored.
+    /// Returns the number of interpolated string ranges stored.
     #[inline]
     pub fn len(&self) -> usize {
         self.raw.len()
@@ -79,18 +79,21 @@ impl FStringRanges {
 }
 
 #[derive(Default)]
-pub(crate) struct FStringRangesBuilder {
+pub(crate) struct InterpolatedStringRangesBuilder {
     start_locations: Vec<TextSize>,
     raw: BTreeMap<TextSize, TextRange>,
 }
 
-impl FStringRangesBuilder {
+impl InterpolatedStringRangesBuilder {
     pub(crate) fn visit_token(&mut self, token: &Token) {
+        // While the logic of this visitor makes it seem possible to pair, say,
+        // an `FStringStart` with a `TStringEnd`, it is not actually possible to
+        // encounter this in tokenized code free from lexical errors.
         match token.kind() {
-            TokenKind::FStringStart => {
+            TokenKind::FStringStart | TokenKind::TStringStart => {
                 self.start_locations.push(token.start());
             }
-            TokenKind::FStringEnd => {
+            TokenKind::FStringEnd | TokenKind::TStringEnd => {
                 if let Some(start) = self.start_locations.pop() {
                     self.raw.insert(start, TextRange::new(start, token.end()));
                 }
@@ -99,7 +102,7 @@ impl FStringRangesBuilder {
         }
     }
 
-    pub(crate) fn finish(self) -> FStringRanges {
-        FStringRanges { raw: self.raw }
+    pub(crate) fn finish(self) -> InterpolatedStringRanges {
+        InterpolatedStringRanges { raw: self.raw }
     }
 }
diff --git a/crates/ruff_python_index/src/lib.rs b/crates/ruff_python_index/src/lib.rs
index aabdef1d48..626585c3d4 100644
--- a/crates/ruff_python_index/src/lib.rs
+++ b/crates/ruff_python_index/src/lib.rs
@@ -1,5 +1,5 @@
-mod fstring_ranges;
 mod indexer;
+mod interpolated_string_ranges;
 mod multiline_ranges;
 
 pub use indexer::Indexer;