diff --git a/crates/ruff_linter/resources/test/fixtures/refurb/FURB168.py b/crates/ruff_linter/resources/test/fixtures/refurb/FURB168.py
index 17238d520c..a9f31e3a78 100644
--- a/crates/ruff_linter/resources/test/fixtures/refurb/FURB168.py
+++ b/crates/ruff_linter/resources/test/fixtures/refurb/FURB168.py
@@ -85,3 +85,10 @@ def _():
 
     if isinstance(foo, type(None)):
         ...
+
+# https://github.com/astral-sh/ruff/issues/19047
+if isinstance(foo, ()):
+    pass
+
+if isinstance(foo, Union[()]):
+    pass
diff --git a/crates/ruff_linter/src/rules/refurb/rules/isinstance_type_none.rs b/crates/ruff_linter/src/rules/refurb/rules/isinstance_type_none.rs
index 793e0968ad..4ff1f1c4af 100644
--- a/crates/ruff_linter/src/rules/refurb/rules/isinstance_type_none.rs
+++ b/crates/ruff_linter/src/rules/refurb/rules/isinstance_type_none.rs
@@ -100,7 +100,9 @@ fn is_none(expr: &Expr, semantic: &SemanticModel) -> bool {
             }
 
             // Ex) `(type(None),)`
-            Expr::Tuple(tuple) => tuple.iter().all(|element| inner(element, false, semantic)),
+            Expr::Tuple(tuple) => {
+                !tuple.is_empty() && tuple.iter().all(|element| inner(element, false, semantic))
+            }
 
             // Ex) `type(None) | type(None)`
             Expr::BinOp(ast::ExprBinOp {
@@ -125,7 +127,8 @@ fn is_none(expr: &Expr, semantic: &SemanticModel) -> bool {
 
                 match slice.as_ref() {
                     Expr::Tuple(ast::ExprTuple { elts, .. }) => {
-                        elts.iter().all(|element| inner(element, true, semantic))
+                        !elts.is_empty()
+                            && elts.iter().all(|element| inner(element, true, semantic))
                     }
                     slice => inner(slice, true, semantic),
                 }