diff --git a/Makefile.pre.in b/Makefile.pre.in
index cffb1a1e4c8..3ddeedf10b9 100644
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -94,7 +94,7 @@ PY_CFLAGS_NODIST=$(CONFIGURE_CFLAGS_NODIST) $(CFLAGS_NODIST)
 # Both CPPFLAGS and LDFLAGS need to contain the shell's value for setup.py to
 # be able to build extension modules using the directories specified in the
 # environment variables
-PY_CPPFLAGS=	$(BASECPPFLAGS) -I. -IInclude -I$(srcdir)/Include $(CONFIGURE_CPPFLAGS) $(CPPFLAGS)
+PY_CPPFLAGS=	$(BASECPPFLAGS) -I. -I$(srcdir)/Include $(CONFIGURE_CPPFLAGS) $(CPPFLAGS)
 PY_LDFLAGS=	$(CONFIGURE_LDFLAGS) $(LDFLAGS)
 NO_AS_NEEDED=	@NO_AS_NEEDED@
 LDLAST=		@LDLAST@
diff --git a/Misc/NEWS b/Misc/NEWS
index 607c15fa95b..ac89f65ad72 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -13,6 +13,12 @@ Core and Builtins
 Library
 -------
 
+Build
+-----
+
+- Issue #15819: Remove redundant include search directory option for building
+  outside the source tree.
+
 Tools/Demos
 -----------