diff --git a/Lib/test/support/__init__.py b/Lib/test/support/__init__.py
index bc263b3033e..ff7db991589 100644
--- a/Lib/test/support/__init__.py
+++ b/Lib/test/support/__init__.py
@@ -986,6 +986,25 @@ TEST_HOME_DIR = os.path.dirname(TEST_SUPPORT_DIR)
 # TEST_DATA_DIR is used as a target download location for remote resources
 TEST_DATA_DIR = os.path.join(TEST_HOME_DIR, "data")
 
+
+def darwin_malloc_err_warning(test_name):
+    """Assure user that loud errors generated by macOS libc's malloc are
+    expected."""
+    if sys.platform != 'darwin':
+        return
+
+    import shutil
+    msg = ' NOTICE '
+    detail = (f'{test_name} may generate "malloc can\'t allocate region"\n'
+              'warnings on macOS systems. This behavior is known. Do not\n'
+              'report a bug unless tests are also failing. See bpo-40928.')
+
+    padding, _ = shutil.get_terminal_size()
+    print(msg.center(padding, '-'))
+    print(detail)
+    print('-' * padding)
+
+
 def findfile(filename, subdir=None):
     """Try to find a file on sys.path or in the test directory.  If it is not
     found the argument passed to the function is returned (this does not
diff --git a/Lib/test/test_decimal.py b/Lib/test/test_decimal.py
index fd62f37de18..d37c53da2cf 100644
--- a/Lib/test/test_decimal.py
+++ b/Lib/test/test_decimal.py
@@ -35,12 +35,17 @@ import locale
 from test.support import (run_unittest, run_doctest, is_resource_enabled,
                           requires_IEEE_754, requires_docstrings)
 from test.support import (import_fresh_module, TestFailed,
-                          run_with_locale, cpython_only)
+                          run_with_locale, cpython_only,
+                          darwin_malloc_err_warning)
 import random
 import inspect
 import threading
 
 
+if sys.platform == 'darwin':
+    darwin_malloc_err_warning('test_decimal')
+
+
 C = import_fresh_module('decimal', fresh=['_decimal'])
 P = import_fresh_module('decimal', blocked=['_decimal'])
 orig_sys_decimal = sys.modules['decimal']
diff --git a/Misc/NEWS.d/next/Tests/2021-08-06-00-07-15.bpo-40928.aIwb6G.rst b/Misc/NEWS.d/next/Tests/2021-08-06-00-07-15.bpo-40928.aIwb6G.rst
new file mode 100644
index 00000000000..c9a5e1b01e5
--- /dev/null
+++ b/Misc/NEWS.d/next/Tests/2021-08-06-00-07-15.bpo-40928.aIwb6G.rst
@@ -0,0 +1,2 @@
+Notify users running test_decimal regression tests on macOS of potential
+harmless "malloc can't allocate region" messages spewed by test_decimal.