diff --git a/Misc/NEWS b/Misc/NEWS
index ac86186b47c..9797b91e8be 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -659,6 +659,9 @@ Build
   the "bin" directory inside the framework is on the shell's search path. This
   feature now also supports the ZSH shell.
 
+- Issue #7473: avoid link errors when building a framework with a different
+  set of architectures than the one that is currently installed.
+
 Tests
 -----
 - Issue #9628: fix runtests.sh -x option so more than one test can be excluded.
diff --git a/setup.py b/setup.py
index cdb1937556c..2eb4b8549b2 100644
--- a/setup.py
+++ b/setup.py
@@ -378,7 +378,12 @@ class PyBuildExt(build_ext):
                     for directory in reversed(options.dirs):
                         add_dir_to_list(dir_list, directory)
 
-        if os.path.normpath(sys.prefix) != '/usr':
+        if os.path.normpath(sys.prefix) != '/usr' \
+                and not sysconfig.get_config_var('PYTHONFRAMEWORK'):
+            # OSX note: Don't add LIBDIR and INCLUDEDIR to building a framework
+            # (PYTHONFRAMEWORK is set) to avoid # linking problems when
+            # building a framework with different architectures than
+            # the one that is currently installed (issue #7473)
             add_dir_to_list(self.compiler.library_dirs,
                             sysconfig.get_config_var("LIBDIR"))
             add_dir_to_list(self.compiler.include_dirs,