diff --git a/Misc/NEWS b/Misc/NEWS
index 106b08a419e..8f4e485f61c 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -76,6 +76,8 @@ Core and Builtins
 Library
 -------
 
+- Issue #1581476: Always use the Tcl global namespace when calling into Tcl.
+
 - Issue #2047: shutil.move() could believe that its destination path was
   inside its source path if it began with the same letters (e.g. "src" vs.
   "src.new").
diff --git a/Modules/_tkinter.c b/Modules/_tkinter.c
index f101450de36..c1060f6d4cb 100644
--- a/Modules/_tkinter.c
+++ b/Modules/_tkinter.c
@@ -1284,8 +1284,7 @@ Tkapp_Call(PyObject *selfptr, PyObject *args)
 	int objc, i;
 	PyObject *res = NULL;
 	TkappObject *self = (TkappObject*)selfptr;
-	/* Could add TCL_EVAL_GLOBAL if wrapped by GlobalCall... */
-	int flags = TCL_EVAL_DIRECT;
+	int flags = TCL_EVAL_DIRECT | TCL_EVAL_GLOBAL;
 
 	/* If args is a single tuple, replace with contents of tuple */
 	if (1 == PyTuple_Size(args)){