diff --git a/Python/instruction_sequence.c b/Python/instruction_sequence.c
index d843d5f1690..3a254b2c9de 100644
--- a/Python/instruction_sequence.c
+++ b/Python/instruction_sequence.c
@@ -158,6 +158,8 @@ _PyInstructionSequence_AddNested(instr_sequence *seq, instr_sequence *nested)
 
 void
 PyInstructionSequence_Fini(instr_sequence *seq) {
+    Py_XDECREF(seq->s_nested);
+
     PyMem_Free(seq->s_labelmap);
     seq->s_labelmap = NULL;