diff --git a/crates/ruff_linter/resources/test/fixtures/refurb/FURB105.py b/crates/ruff_linter/resources/test/fixtures/refurb/FURB105.py
index 86a6584f3a..aca23813b3 100644
--- a/crates/ruff_linter/resources/test/fixtures/refurb/FURB105.py
+++ b/crates/ruff_linter/resources/test/fixtures/refurb/FURB105.py
@@ -19,6 +19,9 @@ print("", *args, sep="")
 print("", **kwargs)
 print(sep="\t")
 print(sep=print(1))
+print(f"")
+print(f"", sep=",")
+print(f"", end="bar")
 
 # OK.
 
@@ -33,3 +36,4 @@ print("foo", "", sep=",")
 print("foo", "", "bar", "", sep=",")
 print("", "", **kwargs)
 print(*args, sep=",")
+print(f"foo")
diff --git a/crates/ruff_linter/src/rules/refurb/rules/print_empty_string.rs b/crates/ruff_linter/src/rules/refurb/rules/print_empty_string.rs
index 2b8ecfab45..6c010da313 100644
--- a/crates/ruff_linter/src/rules/refurb/rules/print_empty_string.rs
+++ b/crates/ruff_linter/src/rules/refurb/rules/print_empty_string.rs
@@ -1,5 +1,5 @@
 use ruff_macros::{ViolationMetadata, derive_message_formats};
-use ruff_python_ast::helpers::contains_effect;
+use ruff_python_ast::helpers::{contains_effect, is_empty_f_string};
 use ruff_python_ast::{self as ast, Expr};
 use ruff_python_codegen::Generator;
 use ruff_python_semantic::SemanticModel;
@@ -194,13 +194,11 @@ pub(crate) fn print_empty_string(checker: &Checker, call: &ast::ExprCall) {
 
 /// Check if an expression is a constant empty string.
 fn is_empty_string(expr: &Expr) -> bool {
-    matches!(
-        expr,
-        Expr::StringLiteral(ast::ExprStringLiteral {
-            value,
-            ..
-        }) if value.is_empty()
-    )
+    match expr {
+        Expr::StringLiteral(ast::ExprStringLiteral { value, .. }) => value.is_empty(),
+        Expr::FString(f_string) => is_empty_f_string(f_string),
+        _ => false,
+    }
 }
 
 #[derive(Debug, Clone, Copy, PartialEq, Eq)]
diff --git a/crates/ruff_linter/src/rules/refurb/snapshots/ruff_linter__rules__refurb__tests__FURB105_FURB105.py.snap b/crates/ruff_linter/src/rules/refurb/snapshots/ruff_linter__rules__refurb__tests__FURB105_FURB105.py.snap
index e258e208cb..d875fcff56 100644
--- a/crates/ruff_linter/src/rules/refurb/snapshots/ruff_linter__rules__refurb__tests__FURB105_FURB105.py.snap
+++ b/crates/ruff_linter/src/rules/refurb/snapshots/ruff_linter__rules__refurb__tests__FURB105_FURB105.py.snap
@@ -317,7 +317,7 @@ help: Remove empty string
 19 + print(**kwargs)
 20 | print(sep="\t")
 21 | print(sep=print(1))
-22 | 
+22 | print(f"")
 
 FURB105 [*] Unnecessary separator passed to `print`
   --> FURB105.py:20:1
@@ -327,6 +327,7 @@ FURB105 [*] Unnecessary separator passed to `print`
 20 | print(sep="\t")
    | ^^^^^^^^^^^^^^^
 21 | print(sep=print(1))
+22 | print(f"")
    |
 help: Remove separator
 17 | print("", *args)
@@ -335,8 +336,8 @@ help: Remove separator
    - print(sep="\t")
 20 + print()
 21 | print(sep=print(1))
-22 | 
-23 | # OK.
+22 | print(f"")
+23 | print(f"", sep=",")
 
 FURB105 [*] Unnecessary separator passed to `print`
   --> FURB105.py:21:1
@@ -345,8 +346,8 @@ FURB105 [*] Unnecessary separator passed to `print`
 20 | print(sep="\t")
 21 | print(sep=print(1))
    | ^^^^^^^^^^^^^^^^^^^
-22 |
-23 | # OK.
+22 | print(f"")
+23 | print(f"", sep=",")
    |
 help: Remove separator
 18 | print("", *args, sep="")
@@ -354,7 +355,66 @@ help: Remove separator
 20 | print(sep="\t")
    - print(sep=print(1))
 21 + print()
-22 | 
-23 | # OK.
-24 | 
+22 | print(f"")
+23 | print(f"", sep=",")
+24 | print(f"", end="bar")
 note: This is an unsafe fix and may change runtime behavior
+
+FURB105 [*] Unnecessary empty string passed to `print`
+  --> FURB105.py:22:1
+   |
+20 | print(sep="\t")
+21 | print(sep=print(1))
+22 | print(f"")
+   | ^^^^^^^^^^
+23 | print(f"", sep=",")
+24 | print(f"", end="bar")
+   |
+help: Remove empty string
+19 | print("", **kwargs)
+20 | print(sep="\t")
+21 | print(sep=print(1))
+   - print(f"")
+22 + print()
+23 | print(f"", sep=",")
+24 | print(f"", end="bar")
+25 | 
+
+FURB105 [*] Unnecessary empty string and separator passed to `print`
+  --> FURB105.py:23:1
+   |
+21 | print(sep=print(1))
+22 | print(f"")
+23 | print(f"", sep=",")
+   | ^^^^^^^^^^^^^^^^^^^
+24 | print(f"", end="bar")
+   |
+help: Remove empty string and separator
+20 | print(sep="\t")
+21 | print(sep=print(1))
+22 | print(f"")
+   - print(f"", sep=",")
+23 + print()
+24 | print(f"", end="bar")
+25 | 
+26 | # OK.
+
+FURB105 [*] Unnecessary empty string passed to `print`
+  --> FURB105.py:24:1
+   |
+22 | print(f"")
+23 | print(f"", sep=",")
+24 | print(f"", end="bar")
+   | ^^^^^^^^^^^^^^^^^^^^^
+25 |
+26 | # OK.
+   |
+help: Remove empty string
+21 | print(sep=print(1))
+22 | print(f"")
+23 | print(f"", sep=",")
+   - print(f"", end="bar")
+24 + print(end="bar")
+25 | 
+26 | # OK.
+27 |