diff --git a/docs/guides/scripts.md b/docs/guides/scripts.md
index dcba78666..072dc8962 100644
--- a/docs/guides/scripts.md
+++ b/docs/guides/scripts.md
@@ -1 +1,178 @@
-# Running a script
+# Running scripts
+
+A Python script is a file intended for standalone execution, e.g., with `python <script>.py`. Using uv to execute scripts will ensure that
+script dependencies are properly managed inside and outside of projects.
+
+## Running a script without dependencies
+
+If a script has no dependencies, it can be executed with `uv run`:
+
+```python
+print("Hello world")
+```
+
+```console
+$ uv run example.py
+Hello world
+```
+
+Similarly, if the script depends on a module in the standard library, there's nothing more to do:
+
+```python
+import os
+
+print(os.path.expanduser("~"))
+```
+
+```console
+$ uv run example.py
+/Users/astral
+```
+
+Arguments can be passed to the script:
+
+```python
+import sys
+
+print(" ".join(sys.argv[1:]))
+```
+
+```console
+$ uv run example.py test
+test
+
+$ uv run example.py hello world!
+hello world!
+```
+
+Note that if `uv run` is used in a _project_, i.e. a directory with a `pyproject.toml`, it will install the current project before running the script. If the script does not depend on the project, use the `--isolated` flag to skip this:
+
+```console
+# Note, it is important that the flag comes _before_ the script
+$ uv run --isolated example.py
+```
+
+See the [projects](./projects.md) guide for more details on working in projects.
+
+## Running a script with dependencies
+
+When a script requires dependencies, they must be installed into the environment that the script runs in. uv prefers to create these environments on-demand instead of maintaining a long-lived virtual environment with manually managed dependencies. This requires explicit declaration
+of dependencies that are required for the script. Generally, it's recommended to use a [project](./projects.md) or [inline metadata](#declaring-script-dependencies) to declare dependencies, but uv supports requesting dependencies per invocation as well.
+
+For example, the following script requires `rich`.
+
+```python
+import time
+from rich.progress import track
+
+for i in track(range(20), description="For example:"):
+    time.sleep(0.05)
+```
+
+If executed without specifying a dependency, this script will fail:
+
+```console
+$ uv run --isolated example.py
+Traceback (most recent call last):
+  File "/Users/astral/example.py", line 2, in <module>
+    from rich.progress import track
+ModuleNotFoundError: No module named 'rich'
+```
+
+The dependency can be requested with the `--with` option:
+
+```console
+$ uv run --with rich example.py
+For example: ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 100% 0:00:01
+```
+
+Constraints can be added to the requested dependency if specific versions are needed:
+
+```consoleq
+$ uv run --with 'rich>12,<13' example.py
+```
+
+Multiple dependencies can be requested by repeating with `--with` option.
+
+Note that if `uv run` is used in a _project_, these dependencies will be included _in addition_ to the project's dependencies. To opt-out of this behavior, use the `--isolated` flag.
+
+## Declaring script dependencies
+
+Python recently added a standard format for [inline script metadata](https://packaging.python.org/en/latest/specifications/inline-script-metadata/#inline-script-metadata). This allows the dependencies for a script to be declared in the script itself.
+
+To use inline script metadata, include a `script` section at the top of the script:
+
+```python
+# /// script
+# dependencies = [
+#   "requests<3",
+#   "rich",
+# ]
+# ///
+
+import requests
+from rich.pretty import pprint
+
+resp = requests.get("https://peps.python.org/api/peps.json")
+data = resp.json()
+pprint([(k, v["title"]) for k, v in data.items()][:10])
+```
+
+uv will automatically create an environment with the dependencies necessary to run the script, e.g.:
+
+```console
+$ uv run example.py
+[
+│   ('1', 'PEP Purpose and Guidelines'),
+│   ('2', 'Procedure for Adding New Modules'),
+│   ('3', 'Guidelines for Handling Bug Reports'),
+│   ('4', 'Deprecation of Standard Modules'),
+│   ('5', 'Guidelines for Language Evolution'),
+│   ('6', 'Bug Fix Releases'),
+│   ('7', 'Style Guide for C Code'),
+│   ('8', 'Style Guide for Python Code'),
+│   ('9', 'Sample Plaintext PEP Template'),
+│   ('10', 'Voting Guidelines')
+]
+```
+
+uv also supports Python version requirements:
+
+```python
+# /// script
+# requires-python = ">=3.12"
+# dependencies = []
+# ///
+
+# Use some syntax added in Python 3.12
+type Point = tuple[float, float]
+print(Point)
+```
+
+uv will fetch the required Python version if it is not installed — see the documentation on [Python versions](../python-versions.md) for more details. Note that the `dependencies` field must be provided even if empty.
+
+Note that when using inline script metadata, even if `uv run` is used in a _project_, the project's dependencies will be ignored. The `--isolated` flag is not required.
+
+## Using different Python versions
+
+uv allows arbitrary Python versions to be requested on each script invocation, for example:
+
+```python
+import sys
+
+print(".".join(map(str, sys.version_info[:3])))
+```
+
+```console
+# Use the default Python version, may differ on your machine
+$ uv run example.py
+3.12.1
+```
+
+```console
+# Use a specific Python version
+$ uv run --python 3.10 example.py
+3.10.13
+```
+
+See the [Python versions](../python-versions.md) documentation for more details on requesting Python versions.