diff --git a/crates/distribution-types/src/index_url.rs b/crates/distribution-types/src/index_url.rs
index 1d9b7e120..ad11ca87e 100644
--- a/crates/distribution-types/src/index_url.rs
+++ b/crates/distribution-types/src/index_url.rs
@@ -386,6 +386,11 @@ impl<'a> IndexLocations {
         self.flat_index.iter()
     }
 
+    /// Return the `--no-index` flag.
+    pub fn no_index(&self) -> bool {
+        self.no_index
+    }
+
     /// Clone the index locations into a [`IndexUrls`] instance.
     pub fn index_urls(&'a self) -> IndexUrls {
         IndexUrls {
diff --git a/crates/uv/src/commands/project/environment.rs b/crates/uv/src/commands/project/environment.rs
index 74adf6bae..bfc7b0ef1 100644
--- a/crates/uv/src/commands/project/environment.rs
+++ b/crates/uv/src/commands/project/environment.rs
@@ -3,7 +3,6 @@ use tracing::debug;
 
 use cache_key::digest;
 use distribution_types::Resolution;
-use pypi_types::Requirement;
 use uv_cache::{Cache, CacheBucket};
 use uv_client::Connectivity;
 use uv_configuration::{Concurrency, PreviewMode};
@@ -30,7 +29,7 @@ impl CachedEnvironment {
     /// Get or create an [`CachedEnvironment`] based on a given set of requirements and a base
     /// interpreter.
     pub(crate) async fn get_or_create(
-        requirements: Vec<Requirement>,
+        spec: RequirementsSpecification,
         interpreter: Interpreter,
         settings: &ResolverInstallerSettings,
         state: &SharedState,
@@ -41,8 +40,6 @@ impl CachedEnvironment {
         cache: &Cache,
         printer: Printer,
     ) -> anyhow::Result<Self> {
-        let spec = RequirementsSpecification::from_requirements(requirements);
-
         // When caching, always use the base interpreter, rather than that of the virtual
         // environment.
         let interpreter = if let Some(interpreter) = interpreter.to_base_interpreter(cache)? {
diff --git a/crates/uv/src/commands/project/mod.rs b/crates/uv/src/commands/project/mod.rs
index d1a5f3262..cfe469c6b 100644
--- a/crates/uv/src/commands/project/mod.rs
+++ b/crates/uv/src/commands/project/mod.rs
@@ -26,7 +26,7 @@ use uv_resolver::{
     FlatIndex, OptionsBuilder, PythonRequirement, RequiresPython, ResolutionGraph, ResolverMarkers,
 };
 use uv_types::{BuildIsolation, EmptyInstalledPackages, HashStrategy};
-use uv_warnings::warn_user;
+use uv_warnings::{warn_user, warn_user_once};
 use uv_workspace::Workspace;
 
 use crate::commands::pip::operations::Modifications;
@@ -405,6 +405,8 @@ pub(crate) async fn resolve_environment<'a>(
     cache: &Cache,
     printer: Printer,
 ) -> anyhow::Result<ResolutionGraph> {
+    warn_on_requirements_txt_setting(&spec, settings);
+
     let ResolverSettingsRef {
         index_locations,
         index_strategy,
@@ -418,6 +420,16 @@ pub(crate) async fn resolve_environment<'a>(
         build_options,
     } = settings;
 
+    // Respect all requirements from the provided sources.
+    let RequirementsSpecification {
+        project,
+        requirements,
+        constraints,
+        overrides,
+        source_trees,
+        ..
+    } = spec;
+
     // Determine the tags, markers, and interpreter to use for resolution.
     let tags = interpreter.tags()?;
     let markers = interpreter.markers();
@@ -490,12 +502,12 @@ pub(crate) async fn resolve_environment<'a>(
 
     // Resolve the requirements.
     Ok(pip::operations::resolve(
-        spec.requirements,
-        spec.constraints,
-        spec.overrides,
+        requirements,
+        constraints,
+        overrides,
         dev,
-        spec.source_trees,
-        spec.project,
+        source_trees,
+        project,
         &extras,
         preferences,
         EmptyInstalledPackages,
@@ -644,6 +656,8 @@ pub(crate) async fn update_environment(
     cache: &Cache,
     printer: Printer,
 ) -> anyhow::Result<PythonEnvironment> {
+    warn_on_requirements_txt_setting(&spec, settings.as_ref().into());
+
     let ResolverInstallerSettings {
         index_locations,
         index_strategy,
@@ -659,14 +673,20 @@ pub(crate) async fn update_environment(
         build_options,
     } = settings;
 
+    // Respect all requirements from the provided sources.
+    let RequirementsSpecification {
+        project,
+        requirements,
+        constraints,
+        overrides,
+        source_trees,
+        ..
+    } = spec;
+
     // Check if the current environment satisfies the requirements
     let site_packages = SitePackages::from_environment(&venv)?;
-    if spec.source_trees.is_empty()
-        && reinstall.is_none()
-        && upgrade.is_none()
-        && spec.overrides.is_empty()
-    {
-        match site_packages.satisfies(&spec.requirements, &spec.constraints)? {
+    if source_trees.is_empty() && reinstall.is_none() && upgrade.is_none() && overrides.is_empty() {
+        match site_packages.satisfies(&requirements, &constraints)? {
             // If the requirements are already satisfied, we're done.
             SatisfiesResult::Fresh {
                 recursive_requirements,
@@ -756,12 +776,12 @@ pub(crate) async fn update_environment(
 
     // Resolve the requirements.
     let resolution = match pip::operations::resolve(
-        spec.requirements,
-        spec.constraints,
-        spec.overrides,
+        requirements,
+        constraints,
+        overrides,
         dev,
-        spec.source_trees,
-        spec.project,
+        source_trees,
+        project,
         &extras,
         preferences,
         site_packages.clone(),
@@ -816,3 +836,62 @@ pub(crate) async fn update_environment(
 
     Ok(venv)
 }
+
+/// Warn if the user provides (e.g.) an `--index-url` in a requirements file.
+fn warn_on_requirements_txt_setting(
+    spec: &RequirementsSpecification,
+    settings: ResolverSettingsRef<'_>,
+) {
+    let RequirementsSpecification {
+        index_url,
+        extra_index_urls,
+        no_index,
+        find_links,
+        no_binary,
+        no_build,
+        ..
+    } = spec;
+
+    if settings.index_locations.no_index() {
+        // Nothing to do, we're ignoring the URLs anyway.
+    } else if *no_index {
+        warn_user_once!("Ignoring `--no-index` from requirements file. Instead, use the `--no-index` command-line argument, or set `no-index` in a `uv.toml` or `pyproject.toml` file.");
+    } else {
+        if let Some(index_url) = index_url {
+            if settings.index_locations.index() != Some(index_url) {
+                warn_user_once!(
+                    "Ignoring `--index-url` from requirements file: `{}`. Instead, use the `--index-url` command-line argument, or set `index-url` in a `uv.toml` or `pyproject.toml` file.",
+                    index_url
+                );
+            }
+        }
+        for extra_index_url in extra_index_urls {
+            if !settings
+                .index_locations
+                .extra_index()
+                .contains(extra_index_url)
+            {
+                warn_user_once!(
+                    "Ignoring `--extra-index-url` from requirements file: `{}`. Instead, use the `--extra-index-url` command-line argument, or set `extra-index-url` in a `uv.toml` or `pyproject.toml` file.`",
+                    extra_index_url
+                );
+            }
+        }
+        for find_link in find_links {
+            if !settings.index_locations.flat_index().contains(find_link) {
+                warn_user_once!(
+                    "Ignoring `--find-links` from requirements file: `{}`. Instead, use the `--find-links` command-line argument, or set `find-links` in a `uv.toml` or `pyproject.toml` file.`",
+                    find_link
+                );
+            }
+        }
+    }
+
+    if !no_binary.is_none() && settings.build_options.no_binary() != no_binary {
+        warn_user_once!("Ignoring `--no-binary` setting from requirements file. Instead, use the `--no-binary` command-line argument, or set `no-binary` in a `uv.toml` or `pyproject.toml` file.");
+    }
+
+    if !no_build.is_none() && settings.build_options.no_build() != no_build {
+        warn_user_once!("Ignoring `--no-binary` setting from requirements file. Instead, use the `--no-build` command-line argument, or set `no-build` in a `uv.toml` or `pyproject.toml` file.");
+    }
+}
diff --git a/crates/uv/src/commands/project/run.rs b/crates/uv/src/commands/project/run.rs
index 601753a2c..59313d6ee 100644
--- a/crates/uv/src/commands/project/run.rs
+++ b/crates/uv/src/commands/project/run.rs
@@ -133,8 +133,9 @@ pub(crate) async fn run(
                 .into_iter()
                 .map(Requirement::from)
                 .collect();
+            let spec = RequirementsSpecification::from_requirements(requirements);
             let environment = CachedEnvironment::get_or_create(
-                requirements,
+                spec,
                 interpreter,
                 &settings,
                 &state,
diff --git a/crates/uv/src/commands/tool/common.rs b/crates/uv/src/commands/tool/common.rs
index 8b4ca39f0..7b83a9514 100644
--- a/crates/uv/src/commands/tool/common.rs
+++ b/crates/uv/src/commands/tool/common.rs
@@ -1,54 +1,8 @@
 use distribution_types::{InstalledDist, Name};
-use pypi_types::Requirement;
-use uv_cache::Cache;
-use uv_client::{BaseClientBuilder, Connectivity};
-use uv_configuration::{Concurrency, PreviewMode};
 use uv_installer::SitePackages;
-use uv_python::{Interpreter, PythonEnvironment};
-use uv_requirements::{RequirementsSource, RequirementsSpecification};
+use uv_python::PythonEnvironment;
 use uv_tool::entrypoint_paths;
 
-use crate::commands::{project, SharedState};
-use crate::printer::Printer;
-use crate::settings::ResolverInstallerSettings;
-
-/// Resolve any [`UnnamedRequirements`].
-pub(super) async fn resolve_requirements(
-    requirements: &[RequirementsSource],
-    interpreter: &Interpreter,
-    settings: &ResolverInstallerSettings,
-    state: &SharedState,
-    preview: PreviewMode,
-    connectivity: Connectivity,
-    concurrency: Concurrency,
-    native_tls: bool,
-    cache: &Cache,
-    printer: Printer,
-) -> anyhow::Result<Vec<Requirement>> {
-    let client_builder = BaseClientBuilder::new()
-        .connectivity(connectivity)
-        .native_tls(native_tls);
-
-    // Parse the requirements.
-    let spec =
-        RequirementsSpecification::from_simple_sources(requirements, &client_builder).await?;
-
-    // Resolve the parsed requirements.
-    project::resolve_names(
-        spec.requirements,
-        interpreter,
-        settings,
-        state,
-        preview,
-        connectivity,
-        concurrency,
-        native_tls,
-        cache,
-        printer,
-    )
-    .await
-}
-
 /// Return all packages which contain an executable with the given name.
 pub(super) fn matching_packages(
     name: &str,
diff --git a/crates/uv/src/commands/tool/install.rs b/crates/uv/src/commands/tool/install.rs
index 44f4c3fba..0e2c3ed9a 100644
--- a/crates/uv/src/commands/tool/install.rs
+++ b/crates/uv/src/commands/tool/install.rs
@@ -8,7 +8,7 @@ use itertools::Itertools;
 use owo_colors::OwoColorize;
 use tracing::{debug, warn};
 
-use distribution_types::Name;
+use distribution_types::{Name, UnresolvedRequirementSpecification};
 use pypi_types::Requirement;
 use uv_cache::Cache;
 use uv_client::{BaseClientBuilder, Connectivity};
@@ -28,7 +28,7 @@ use uv_tool::{entrypoint_paths, find_executable_directory, InstalledTools, Tool,
 use uv_warnings::{warn_user, warn_user_once};
 
 use crate::commands::reporters::PythonDownloadReporter;
-use crate::commands::tool::common::resolve_requirements;
+
 use crate::commands::{
     project::{resolve_environment, resolve_names, sync_environment, update_environment},
     tool::common::matching_packages,
@@ -138,13 +138,21 @@ pub(crate) async fn install(
         .unwrap()
     };
 
-    // Combine the `from` and `with` requirements.
+    // Read the `--with` requirements.
+    let spec = {
+        let client_builder = BaseClientBuilder::new()
+            .connectivity(connectivity)
+            .native_tls(native_tls);
+        RequirementsSpecification::from_simple_sources(with, &client_builder).await?
+    };
+
+    // Resolve the `--from` and `--with` requirements.
     let requirements = {
         let mut requirements = Vec::with_capacity(1 + with.len());
         requirements.push(from.clone());
         requirements.extend(
-            resolve_requirements(
-                with,
+            resolve_names(
+                spec.requirements.clone(),
                 &interpreter,
                 &settings,
                 &state,
@@ -236,9 +244,15 @@ pub(crate) async fn install(
         }
     }
 
-    // Resolve the requirements.
-    let state = SharedState::default();
-    let spec = RequirementsSpecification::from_requirements(requirements.clone());
+    // Create a `RequirementsSpecification` from the resolved requirements, to avoid re-resolving.
+    let spec = RequirementsSpecification {
+        requirements: requirements
+            .iter()
+            .cloned()
+            .map(UnresolvedRequirementSpecification::from)
+            .collect(),
+        ..spec
+    };
 
     // TODO(zanieb): Build the environment in the cache directory then copy into the tool directory.
     // This lets us confirm the environment is valid before removing an existing install. However,
diff --git a/crates/uv/src/commands/tool/run.rs b/crates/uv/src/commands/tool/run.rs
index 609d4e108..7fc47a18b 100644
--- a/crates/uv/src/commands/tool/run.rs
+++ b/crates/uv/src/commands/tool/run.rs
@@ -28,7 +28,8 @@ use uv_tool::{entrypoint_paths, InstalledTools};
 use uv_warnings::{warn_user, warn_user_once};
 
 use crate::commands::reporters::PythonDownloadReporter;
-use crate::commands::tool::common::resolve_requirements;
+
+use crate::commands::project::resolve_names;
 use crate::commands::{
     project, project::environment::CachedEnvironment, tool::common::matching_packages,
 };
@@ -332,13 +333,21 @@ async fn get_or_create_environment(
         .unwrap()
     };
 
-    // Combine the `from` and `with` requirements.
+    // Read the `--with` requirements.
+    let spec = {
+        let client_builder = BaseClientBuilder::new()
+            .connectivity(connectivity)
+            .native_tls(native_tls);
+        RequirementsSpecification::from_simple_sources(with, &client_builder).await?
+    };
+
+    // Resolve the `--from` and `--with` requirements.
     let requirements = {
         let mut requirements = Vec::with_capacity(1 + with.len());
         requirements.push(from.clone());
         requirements.extend(
-            resolve_requirements(
-                with,
+            resolve_names(
+                spec.requirements.clone(),
                 &interpreter,
                 settings,
                 &state,
@@ -388,11 +397,20 @@ async fn get_or_create_environment(
         }
     }
 
+    // Create a `RequirementsSpecification` from the resolved requirements, to avoid re-resolving.
+    let spec = RequirementsSpecification {
+        requirements: requirements
+            .into_iter()
+            .map(UnresolvedRequirementSpecification::from)
+            .collect(),
+        ..spec
+    };
+
     // TODO(zanieb): When implementing project-level tools, discover the project and check if it has the tool.
     // TODO(zanieb): Determine if we should layer on top of the project environment if it is present.
 
     let environment = CachedEnvironment::get_or_create(
-        requirements,
+        spec,
         interpreter,
         settings,
         &state,
diff --git a/crates/uv/src/settings.rs b/crates/uv/src/settings.rs
index 61b9c375f..aa1ae5e72 100644
--- a/crates/uv/src/settings.rs
+++ b/crates/uv/src/settings.rs
@@ -1478,7 +1478,7 @@ pub(crate) struct ResolverSettings {
     pub(crate) build_options: BuildOptions,
 }
 
-#[derive(Debug, Clone)]
+#[derive(Debug, Clone, Copy)]
 pub(crate) struct ResolverSettingsRef<'a> {
     pub(crate) index_locations: &'a IndexLocations,
     pub(crate) index_strategy: IndexStrategy,
diff --git a/crates/uv/tests/run.rs b/crates/uv/tests/run.rs
index 815d98661..73d5b17da 100644
--- a/crates/uv/tests/run.rs
+++ b/crates/uv/tests/run.rs
@@ -718,3 +718,54 @@ fn run_requirements_txt() -> Result<()> {
 
     Ok(())
 }
+
+/// Ignore and warn when (e.g.) the `--index-url` argument is a provided `requirements.txt`.
+#[test]
+fn run_requirements_txt_arguments() -> Result<()> {
+    let context = TestContext::new("3.12");
+
+    let pyproject_toml = context.temp_dir.child("pyproject.toml");
+    pyproject_toml.write_str(indoc! { r#"
+        [project]
+        name = "foo"
+        version = "1.0.0"
+        requires-python = ">=3.8"
+        dependencies = ["typing_extensions"]
+        "#
+    })?;
+
+    let test_script = context.temp_dir.child("main.py");
+    test_script.write_str(indoc! { r"
+        import typing_extensions
+       "
+    })?;
+
+    // Requesting an unsatisfied requirement should install it.
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt.write_str(indoc! { r"
+        --index-url https://test.pypi.org/simple
+        idna
+        "
+    })?;
+
+    uv_snapshot!(context.filters(), context.run().arg("--with-requirements").arg(requirements_txt.as_os_str()).arg("main.py"), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv run` is experimental and may change without warning
+    Resolved 2 packages in [TIME]
+    Prepared 2 packages in [TIME]
+    Installed 2 packages in [TIME]
+     + foo==1.0.0 (from file://[TEMP_DIR]/)
+     + typing-extensions==4.10.0
+    warning: Ignoring `--index-url` from requirements file: `https://test.pypi.org/simple`. Instead, use the `--index-url` command-line argument, or set `index-url` in a `uv.toml` or `pyproject.toml` file.
+    Resolved 1 package in [TIME]
+    Prepared 1 package in [TIME]
+    Installed 1 package in [TIME]
+     + idna==3.6
+    "###);
+
+    Ok(())
+}
diff --git a/crates/uv/tests/tool_install.rs b/crates/uv/tests/tool_install.rs
index 654e7e5ce..e429c3d54 100644
--- a/crates/uv/tests/tool_install.rs
+++ b/crates/uv/tests/tool_install.rs
@@ -7,6 +7,7 @@ use assert_fs::{
     assert::PathAssert,
     fixture::{FileTouch, FileWriteStr, PathChild},
 };
+use indoc::indoc;
 use insta::assert_snapshot;
 use predicates::prelude::predicate;
 
@@ -1373,6 +1374,134 @@ fn tool_install_requirements_txt() {
     });
 }
 
+/// Ignore and warn when (e.g.) the `--index-url` argument is a provided `requirements.txt`.
+#[test]
+fn tool_install_requirements_txt_arguments() {
+    let context = TestContext::new("3.12").with_filtered_exe_suffix();
+    let tool_dir = context.temp_dir.child("tools");
+    let bin_dir = context.temp_dir.child("bin");
+
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt
+        .write_str(indoc! { r"
+        --index-url https://test.pypi.org/simple
+        idna
+        "
+        })
+        .unwrap();
+
+    // Install `black`
+    uv_snapshot!(context.filters(), context.tool_install()
+        .arg("black")
+        .arg("--with-requirements")
+        .arg("requirements.txt")
+        .env("UV_TOOL_DIR", tool_dir.as_os_str())
+        .env("XDG_BIN_HOME", bin_dir.as_os_str())
+        .env("PATH", bin_dir.as_os_str()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv tool install` is experimental and may change without warning
+    warning: Ignoring `--index-url` from requirements file: `https://test.pypi.org/simple`. Instead, use the `--index-url` command-line argument, or set `index-url` in a `uv.toml` or `pyproject.toml` file.
+    Resolved 7 packages in [TIME]
+    Prepared 7 packages in [TIME]
+    Installed 7 packages in [TIME]
+     + black==24.3.0
+     + click==8.1.7
+     + idna==3.6
+     + mypy-extensions==1.0.0
+     + packaging==24.0
+     + pathspec==0.12.1
+     + platformdirs==4.2.0
+    Installed 2 executables: black, blackd
+    "###);
+
+    insta::with_settings!({
+        filters => context.filters(),
+    }, {
+        // We should have a tool receipt
+        assert_snapshot!(fs_err::read_to_string(tool_dir.join("black").join("uv-receipt.toml")).unwrap(), @r###"
+        [tool]
+        requirements = [
+            "black",
+            "idna",
+        ]
+        entrypoints = [
+            { name = "black", install-path = "[TEMP_DIR]/bin/black" },
+            { name = "blackd", install-path = "[TEMP_DIR]/bin/blackd" },
+        ]
+        "###);
+    });
+
+    // Don't warn, though, if the index URL is the same as the default or as settings.
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt
+        .write_str(indoc! { r"
+        --index-url https://pypi.org/simple
+        idna
+        "
+        })
+        .unwrap();
+
+    // Install `black`
+    uv_snapshot!(context.filters(), context.tool_install()
+        .arg("black")
+        .arg("--with-requirements")
+        .arg("requirements.txt")
+        .env("UV_TOOL_DIR", tool_dir.as_os_str())
+        .env("XDG_BIN_HOME", bin_dir.as_os_str())
+        .env("PATH", bin_dir.as_os_str()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv tool install` is experimental and may change without warning
+    Installed 2 executables: black, blackd
+    "###);
+
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt
+        .write_str(indoc! { r"
+        --index-url https://test.pypi.org/simple
+        idna
+        "
+        })
+        .unwrap();
+
+    // Install `flask`
+    uv_snapshot!(context.filters(), context.tool_install()
+        .arg("flask")
+        .arg("--with-requirements")
+        .arg("requirements.txt")
+        .arg("--index-url")
+        .arg("https://test.pypi.org/simple")
+        .env("UV_TOOL_DIR", tool_dir.as_os_str())
+        .env("XDG_BIN_HOME", bin_dir.as_os_str())
+        .env("PATH", bin_dir.as_os_str()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+
+    ----- stderr -----
+    warning: `uv tool install` is experimental and may change without warning
+    Resolved 8 packages in [TIME]
+    Prepared 8 packages in [TIME]
+    Installed 8 packages in [TIME]
+     + blinker==1.7.0
+     + click==8.1.7
+     + flask==3.0.2
+     + idna==2.7
+     + itsdangerous==2.1.2
+     + jinja2==3.1.3
+     + markupsafe==2.1.5
+     + werkzeug==3.0.1
+    Installed 1 executable: flask
+    "###);
+}
+
 /// Test upgrading an already installed tool.
 #[test]
 fn tool_install_upgrade() {
diff --git a/crates/uv/tests/tool_run.rs b/crates/uv/tests/tool_run.rs
index 1de2eb9ce..4c5a27167 100644
--- a/crates/uv/tests/tool_run.rs
+++ b/crates/uv/tests/tool_run.rs
@@ -2,8 +2,8 @@
 
 use assert_cmd::prelude::*;
 use assert_fs::prelude::*;
-
 use common::{uv_snapshot, TestContext};
+use indoc::indoc;
 
 mod common;
 
@@ -663,3 +663,51 @@ fn tool_run_requirements_txt() {
      + werkzeug==3.0.1
     "###);
 }
+
+/// Ignore and warn when (e.g.) the `--index-url` argument is a provided `requirements.txt`.
+#[test]
+fn tool_run_requirements_txt_arguments() {
+    let context = TestContext::new("3.12").with_filtered_counts();
+    let tool_dir = context.temp_dir.child("tools");
+    let bin_dir = context.temp_dir.child("bin");
+
+    let requirements_txt = context.temp_dir.child("requirements.txt");
+    requirements_txt
+        .write_str(indoc! { r"
+        --index-url https://test.pypi.org/simple
+        idna
+        "
+        })
+        .unwrap();
+
+    // We treat arguments before the command as uv arguments
+    uv_snapshot!(context.filters(), context.tool_run()
+        .arg("--with-requirements")
+        .arg("requirements.txt")
+        .arg("flask")
+        .arg("--version")
+        .env("UV_TOOL_DIR", tool_dir.as_os_str())
+        .env("XDG_BIN_HOME", bin_dir.as_os_str()), @r###"
+    success: true
+    exit_code: 0
+    ----- stdout -----
+    Python 3.12.[X]
+    Flask 3.0.2
+    Werkzeug 3.0.1
+
+    ----- stderr -----
+    warning: `uv tool run` is experimental and may change without warning
+    warning: Ignoring `--index-url` from requirements file: `https://test.pypi.org/simple`. Instead, use the `--index-url` command-line argument, or set `index-url` in a `uv.toml` or `pyproject.toml` file.
+    Resolved [N] packages in [TIME]
+    Prepared [N] packages in [TIME]
+    Installed [N] packages in [TIME]
+     + blinker==1.7.0
+     + click==8.1.7
+     + flask==3.0.2
+     + idna==3.6
+     + itsdangerous==2.1.2
+     + jinja2==3.1.3
+     + markupsafe==2.1.5
+     + werkzeug==3.0.1
+    "###);
+}