diff --git a/Cargo.lock b/Cargo.lock
index 1b561f029..8bab8f264 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -4793,6 +4793,14 @@ dependencies = [
  "walkdir",
 ]
 
+[[package]]
+name = "uv-macros"
+version = "0.0.1"
+dependencies = [
+ "quote",
+ "syn 2.0.66",
+]
+
 [[package]]
 name = "uv-normalize"
 version = "0.0.1"
@@ -4903,6 +4911,7 @@ dependencies = [
  "tracing",
  "uv-configuration",
  "uv-fs",
+ "uv-macros",
  "uv-normalize",
  "uv-resolver",
  "uv-toolchain",
diff --git a/Cargo.toml b/Cargo.toml
index 9e4d203d0..e5f887841 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -38,6 +38,7 @@ uv-extract = { path = "crates/uv-extract" }
 uv-fs = { path = "crates/uv-fs" }
 uv-git = { path = "crates/uv-git" }
 uv-installer = { path = "crates/uv-installer" }
+uv-macros = { path = "crates/uv-macros" }
 uv-normalize = { path = "crates/uv-normalize" }
 uv-requirements = { path = "crates/uv-requirements" }
 uv-resolver = { path = "crates/uv-resolver" }
@@ -103,6 +104,7 @@ platform-info = { version = "2.0.2" }
 pubgrub = { git = "https://github.com/astral-sh/pubgrub", rev = "a68cbd1a26e43986a31563e1d127e83bafca3a0c" }
 pyo3 = { version = "0.21.0" }
 pyo3-log = { version = "0.10.0" }
+quote = { version = "1.0.36" }
 rayon = { version = "1.8.0" }
 reflink-copy = { version = "0.1.15" }
 regex = { version = "1.10.2" }
@@ -119,6 +121,7 @@ seahash = { version = "4.1.0" }
 serde = { version = "1.0.197", features = ["derive"] }
 serde_json = { version = "1.0.114" }
 sha2 = { version = "0.10.8" }
+syn = { version = "2.0.66" }
 sys-info = { version = "0.9.1" }
 target-lexicon = {version = "0.12.14" }
 tempfile = { version = "3.9.0" }
@@ -139,10 +142,10 @@ unicode-width = { version = "0.1.11" }
 unscanny = { version = "0.1.0" }
 url = { version = "2.5.0" }
 urlencoding = { version = "2.1.3" }
-wiremock = { version = "0.6.0" }
 walkdir = { version = "2.5.0" }
 which = { version = "6.0.0" }
 winapi = { version = "0.3.9", features = ["fileapi", "handleapi", "ioapiset", "winbase", "winioctl", "winnt"] }
+wiremock = { version = "0.6.0" }
 zip = { version = "0.6.6", default-features = false, features = ["deflate"] }
 
 [workspace.metadata.cargo-shear]
diff --git a/crates/uv-macros/Cargo.toml b/crates/uv-macros/Cargo.toml
new file mode 100644
index 000000000..aafbbffcd
--- /dev/null
+++ b/crates/uv-macros/Cargo.toml
@@ -0,0 +1,11 @@
+[package]
+name = "uv-macros"
+version = "0.0.1"
+edition = "2021"
+
+[lib]
+proc-macro = true
+
+[dependencies]
+quote = { workspace = true }
+syn = { workspace = true }
diff --git a/crates/uv-macros/src/lib.rs b/crates/uv-macros/src/lib.rs
new file mode 100644
index 000000000..c9ceaefbe
--- /dev/null
+++ b/crates/uv-macros/src/lib.rs
@@ -0,0 +1,40 @@
+use proc_macro::TokenStream;
+use quote::quote;
+use syn::{parse_macro_input, DeriveInput};
+
+#[proc_macro_derive(CombineOptions)]
+pub fn derive_combine(input: TokenStream) -> TokenStream {
+    let input = parse_macro_input!(input as DeriveInput);
+    impl_combine(&input)
+}
+
+fn impl_combine(ast: &DeriveInput) -> TokenStream {
+    let name = &ast.ident;
+    let fields = if let syn::Data::Struct(syn::DataStruct {
+        fields: syn::Fields::Named(ref fields),
+        ..
+    }) = ast.data
+    {
+        &fields.named
+    } else {
+        unimplemented!();
+    };
+
+    let combines = fields.iter().map(|f| {
+        let name = &f.ident;
+        quote! {
+            #name: self.#name.combine(other.#name)
+        }
+    });
+
+    let gen = quote! {
+        impl crate::Combine for #name {
+            fn combine(self, other: #name) -> #name {
+                #name {
+                    #(#combines),*
+                }
+            }
+        }
+    };
+    gen.into()
+}
diff --git a/crates/uv-settings/Cargo.toml b/crates/uv-settings/Cargo.toml
index abff2d85e..a6e05c7a0 100644
--- a/crates/uv-settings/Cargo.toml
+++ b/crates/uv-settings/Cargo.toml
@@ -22,6 +22,7 @@ uv-fs = { workspace = true }
 uv-normalize = { workspace = true, features = ["schemars"] }
 uv-resolver = { workspace = true, features = ["schemars"] }
 uv-toolchain = { workspace = true, features = ["schemars"] }
+uv-macros = { workspace = true }
 
 dirs-sys = { workspace = true }
 fs-err = { workspace = true }
diff --git a/crates/uv-settings/src/combine.rs b/crates/uv-settings/src/combine.rs
index 35593b49b..04eac8fb6 100644
--- a/crates/uv-settings/src/combine.rs
+++ b/crates/uv-settings/src/combine.rs
@@ -7,7 +7,7 @@ use uv_configuration::{ConfigSettings, IndexStrategy, KeyringProviderType, Targe
 use uv_resolver::{AnnotationStyle, ExcludeNewer, PreReleaseMode, ResolutionMode};
 use uv_toolchain::PythonVersion;
 
-use crate::{FilesystemOptions, GlobalOptions, Options, PipOptions, ResolverInstallerOptions};
+use crate::{FilesystemOptions, PipOptions};
 
 pub trait Combine {
     /// Combine two values, preferring the values in `self`.
@@ -37,58 +37,6 @@ impl Combine for Option<FilesystemOptions> {
     }
 }
 
-impl Combine for Options {
-    fn combine(self, other: Options) -> Options {
-        Options {
-            globals: self.globals.combine(other.globals),
-            top_level: self.top_level.combine(other.top_level),
-            pip: self.pip.combine(other.pip),
-            override_dependencies: self
-                .override_dependencies
-                .combine(other.override_dependencies),
-        }
-    }
-}
-
-impl Combine for GlobalOptions {
-    fn combine(self, other: GlobalOptions) -> GlobalOptions {
-        GlobalOptions {
-            native_tls: self.native_tls.combine(other.native_tls),
-            offline: self.offline.combine(other.offline),
-            no_cache: self.no_cache.combine(other.no_cache),
-            cache_dir: self.cache_dir.combine(other.cache_dir),
-            preview: self.preview.combine(other.preview),
-        }
-    }
-}
-
-impl Combine for ResolverInstallerOptions {
-    fn combine(self, other: ResolverInstallerOptions) -> ResolverInstallerOptions {
-        ResolverInstallerOptions {
-            index_url: self.index_url.combine(other.index_url),
-            extra_index_url: self.extra_index_url.combine(other.extra_index_url),
-            no_index: self.no_index.combine(other.no_index),
-            find_links: self.find_links.combine(other.find_links),
-            index_strategy: self.index_strategy.combine(other.index_strategy),
-            keyring_provider: self.keyring_provider.combine(other.keyring_provider),
-            resolution: self.resolution.combine(other.resolution),
-            prerelease: self.prerelease.combine(other.prerelease),
-            config_settings: self.config_settings.combine(other.config_settings),
-            exclude_newer: self.exclude_newer.combine(other.exclude_newer),
-            link_mode: self.link_mode.combine(other.link_mode),
-            compile_bytecode: self.compile_bytecode.combine(other.compile_bytecode),
-            upgrade: self.upgrade.combine(other.upgrade),
-            upgrade_package: self.upgrade_package.combine(other.upgrade_package),
-            reinstall: self.reinstall.combine(other.reinstall),
-            reinstall_package: self.reinstall_package.combine(other.reinstall_package),
-            no_build: self.no_build.combine(other.no_build),
-            no_build_package: self.no_build_package.combine(other.no_build_package),
-            no_binary: self.no_binary.combine(other.no_binary),
-            no_binary_package: self.no_binary_package.combine(other.no_binary_package),
-        }
-    }
-}
-
 impl Combine for Option<PipOptions> {
     fn combine(self, other: Option<PipOptions>) -> Option<PipOptions> {
         match (self, other) {
@@ -98,71 +46,6 @@ impl Combine for Option<PipOptions> {
     }
 }
 
-impl Combine for PipOptions {
-    fn combine(self, other: PipOptions) -> PipOptions {
-        PipOptions {
-            python: self.python.combine(other.python),
-            system: self.system.combine(other.system),
-            break_system_packages: self
-                .break_system_packages
-                .combine(other.break_system_packages),
-            target: self.target.combine(other.target),
-            prefix: self.prefix.combine(other.prefix),
-            index_url: self.index_url.combine(other.index_url),
-            extra_index_url: self.extra_index_url.combine(other.extra_index_url),
-            no_index: self.no_index.combine(other.no_index),
-            find_links: self.find_links.combine(other.find_links),
-            index_strategy: self.index_strategy.combine(other.index_strategy),
-            keyring_provider: self.keyring_provider.combine(other.keyring_provider),
-            no_build: self.no_build.combine(other.no_build),
-            no_binary: self.no_binary.combine(other.no_binary),
-            only_binary: self.only_binary.combine(other.only_binary),
-            no_build_isolation: self.no_build_isolation.combine(other.no_build_isolation),
-            strict: self.strict.combine(other.strict),
-            extra: self.extra.combine(other.extra),
-            all_extras: self.all_extras.combine(other.all_extras),
-            no_deps: self.no_deps.combine(other.no_deps),
-            resolution: self.resolution.combine(other.resolution),
-            prerelease: self.prerelease.combine(other.prerelease),
-            output_file: self.output_file.combine(other.output_file),
-            no_strip_extras: self.no_strip_extras.combine(other.no_strip_extras),
-            no_annotate: self.no_annotate.combine(other.no_annotate),
-            no_header: self.no_header.combine(other.no_header),
-            custom_compile_command: self
-                .custom_compile_command
-                .combine(other.custom_compile_command),
-            generate_hashes: self.generate_hashes.combine(other.generate_hashes),
-            legacy_setup_py: self.legacy_setup_py.combine(other.legacy_setup_py),
-            config_settings: self.config_settings.combine(other.config_settings),
-            python_version: self.python_version.combine(other.python_version),
-            python_platform: self.python_platform.combine(other.python_platform),
-            exclude_newer: self.exclude_newer.combine(other.exclude_newer),
-            no_emit_package: self.no_emit_package.combine(other.no_emit_package),
-            emit_index_url: self.emit_index_url.combine(other.emit_index_url),
-            emit_find_links: self.emit_find_links.combine(other.emit_find_links),
-            emit_marker_expression: self
-                .emit_marker_expression
-                .combine(other.emit_marker_expression),
-            emit_index_annotation: self
-                .emit_index_annotation
-                .combine(other.emit_index_annotation),
-            annotation_style: self.annotation_style.combine(other.annotation_style),
-            link_mode: self.link_mode.combine(other.link_mode),
-            compile_bytecode: self.compile_bytecode.combine(other.compile_bytecode),
-            require_hashes: self.require_hashes.combine(other.require_hashes),
-            upgrade: self.upgrade.combine(other.upgrade),
-            upgrade_package: self.upgrade_package.combine(other.upgrade_package),
-            reinstall: self.reinstall.combine(other.reinstall),
-            reinstall_package: self.reinstall_package.combine(other.reinstall_package),
-            concurrent_downloads: self
-                .concurrent_downloads
-                .combine(other.concurrent_downloads),
-            concurrent_builds: self.concurrent_builds.combine(other.concurrent_builds),
-            concurrent_installs: self.concurrent_installs.combine(other.concurrent_installs),
-        }
-    }
-}
-
 macro_rules! impl_combine_or {
     ($name:ident) => {
         impl Combine for Option<$name> {
diff --git a/crates/uv-settings/src/settings.rs b/crates/uv-settings/src/settings.rs
index 2956a8999..f8c2e1224 100644
--- a/crates/uv-settings/src/settings.rs
+++ b/crates/uv-settings/src/settings.rs
@@ -8,6 +8,7 @@ use pypi_types::VerbatimParsedUrl;
 use uv_configuration::{
     ConfigSettings, IndexStrategy, KeyringProviderType, PackageNameSpecifier, TargetTriple,
 };
+use uv_macros::CombineOptions;
 use uv_normalize::{ExtraName, PackageName};
 use uv_resolver::{AnnotationStyle, ExcludeNewer, PreReleaseMode, ResolutionMode};
 use uv_toolchain::PythonVersion;
@@ -28,7 +29,7 @@ pub(crate) struct Tools {
 
 /// A `[tool.uv]` section.
 #[allow(dead_code)]
-#[derive(Debug, Clone, Default, Deserialize)]
+#[derive(Debug, Clone, Default, Deserialize, CombineOptions)]
 #[serde(rename_all = "kebab-case")]
 #[cfg_attr(feature = "schemars", derive(schemars::JsonSchema))]
 pub struct Options {
@@ -49,7 +50,7 @@ pub struct Options {
 
 /// Global settings, relevant to all invocations.
 #[allow(dead_code)]
-#[derive(Debug, Clone, Default, Deserialize)]
+#[derive(Debug, Clone, Default, Deserialize, CombineOptions)]
 #[serde(rename_all = "kebab-case")]
 #[cfg_attr(feature = "schemars", derive(schemars::JsonSchema))]
 pub struct GlobalOptions {
@@ -111,7 +112,7 @@ pub struct ResolverOptions {
 /// Shared settings, relevant to all operations that must resolve and install dependencies. The
 /// union of [`InstallerOptions`] and [`ResolverOptions`].
 #[allow(dead_code)]
-#[derive(Debug, Clone, Default, Deserialize)]
+#[derive(Debug, Clone, Default, Deserialize, CombineOptions)]
 #[serde(rename_all = "kebab-case")]
 #[cfg_attr(feature = "schemars", derive(schemars::JsonSchema))]
 pub struct ResolverInstallerOptions {
@@ -139,7 +140,7 @@ pub struct ResolverInstallerOptions {
 
 /// A `[tool.uv.pip]` section.
 #[allow(dead_code)]
-#[derive(Debug, Clone, Default, Deserialize)]
+#[derive(Debug, Clone, Default, Deserialize, CombineOptions)]
 #[serde(deny_unknown_fields, rename_all = "kebab-case")]
 #[cfg_attr(feature = "schemars", derive(schemars::JsonSchema))]
 pub struct PipOptions {