diff --git a/crates/uv/src/cli.rs b/crates/uv/src/cli.rs
index 4e374fd55..71bd446cc 100644
--- a/crates/uv/src/cli.rs
+++ b/crates/uv/src/cli.rs
@@ -35,11 +35,6 @@ pub(crate) struct Cli {
     /// The path to a `uv.toml` file to use for configuration.
     #[arg(long, env = "UV_CONFIG_FILE", hide = true)]
     pub(crate) config_file: Option<PathBuf>,
-
-    /// Avoid discovering a `pyproject.toml` or `uv.toml` file in the current directory or any
-    /// parent directories.
-    #[arg(long, hide = true)]
-    pub(crate) isolated: bool,
 }
 
 #[derive(Parser, Debug, Clone)]
@@ -92,6 +87,11 @@ pub(crate) struct GlobalArgs {
 
     #[arg(global = true, long, overrides_with("preview"), hide = true)]
     pub(crate) no_preview: bool,
+
+    /// Avoid discovering a `pyproject.toml` or `uv.toml` file in the current directory or any
+    /// parent directories.
+    #[arg(global = true, long, hide = true)]
+    pub(crate) isolated: bool,
 }
 
 #[derive(Debug, Clone, clap::ValueEnum)]
diff --git a/crates/uv/src/main.rs b/crates/uv/src/main.rs
index 7290c7929..5821af0ee 100644
--- a/crates/uv/src/main.rs
+++ b/crates/uv/src/main.rs
@@ -112,7 +112,7 @@ async fn run() -> Result<ExitStatus> {
     // 3. The user configuration file.
     let workspace = if let Some(config_file) = cli.config_file.as_ref() {
         Some(uv_workspace::Workspace::from_file(config_file)?)
-    } else if cli.isolated {
+    } else if cli.global_args.isolated {
         None
     } else {
         let project = uv_workspace::Workspace::find(env::current_dir()?)?;
@@ -524,7 +524,7 @@ async fn run() -> Result<ExitStatus> {
                 args.args,
                 requirements,
                 args.python,
-                cli.isolated,
+                globals.isolated,
                 globals.preview,
                 &cache,
                 printer,
diff --git a/crates/uv/src/settings.rs b/crates/uv/src/settings.rs
index 8cb4a9c3c..3f449a420 100644
--- a/crates/uv/src/settings.rs
+++ b/crates/uv/src/settings.rs
@@ -34,6 +34,7 @@ pub(crate) struct GlobalSettings {
     pub(crate) verbose: u8,
     pub(crate) color: ColorChoice,
     pub(crate) native_tls: bool,
+    pub(crate) isolated: bool,
     pub(crate) preview: PreviewMode,
 }
 
@@ -51,6 +52,7 @@ impl GlobalSettings {
             native_tls: flag(args.native_tls, args.no_native_tls)
                 .or(workspace.and_then(|workspace| workspace.options.native_tls))
                 .unwrap_or(false),
+            isolated: args.isolated,
             preview: PreviewMode::from(
                 flag(args.preview, args.no_preview)
                     .or(workspace.and_then(|workspace| workspace.options.preview))