diff --git a/crates/uv-requirements/src/lookahead.rs b/crates/uv-requirements/src/lookahead.rs
index c0f854cf1..1275352da 100644
--- a/crates/uv-requirements/src/lookahead.rs
+++ b/crates/uv-requirements/src/lookahead.rs
@@ -1,15 +1,17 @@
 use std::collections::VecDeque;
 
 use anyhow::{Context, Result};
+use cache_key::CanonicalUrl;
 use futures::stream::FuturesUnordered;
 use futures::StreamExt;
 use rustc_hash::FxHashSet;
 
-use distribution_types::{Dist, LocalEditable};
+use distribution_types::{Dist, DistributionMetadata, LocalEditable};
 use pep508_rs::{MarkerEnvironment, Requirement, VersionOrUrl};
 use pypi_types::Metadata23;
 use uv_client::RegistryClient;
 use uv_distribution::{DistributionDatabase, Reporter};
+use uv_resolver::InMemoryIndex;
 use uv_types::{BuildContext, Constraints, Overrides, RequestedRequirements};
 
 /// A resolver for resolving lookahead requirements from direct URLs.
@@ -37,6 +39,8 @@ pub struct LookaheadResolver<'a, Context: BuildContext + Send + Sync> {
     overrides: &'a Overrides,
     /// The editable requirements for the project.
     editables: &'a [(LocalEditable, Metadata23)],
+    /// The in-memory index for resolving dependencies.
+    index: &'a InMemoryIndex,
     /// The database for fetching and building distributions.
     database: DistributionDatabase<'a, Context>,
 }
@@ -50,12 +54,14 @@ impl<'a, Context: BuildContext + Send + Sync> LookaheadResolver<'a, Context> {
         editables: &'a [(LocalEditable, Metadata23)],
         context: &'a Context,
         client: &'a RegistryClient,
+        index: &'a InMemoryIndex,
     ) -> Self {
         Self {
             requirements,
             constraints,
             overrides,
             editables,
+            index,
             database: DistributionDatabase::new(client, context),
         }
     }
@@ -126,15 +132,34 @@ impl<'a, Context: BuildContext + Send + Sync> LookaheadResolver<'a, Context> {
         // Convert to a buildable distribution.
         let dist = Dist::from_url(requirement.name, url.clone())?;
 
-        // Run the PEP 517 build process to extract metadata from the source distribution.
-        let (metadata, _precise) = self
-            .database
-            .get_or_build_wheel_metadata(&dist)
-            .await
-            .with_context(|| match &dist {
-                Dist::Built(built) => format!("Failed to download: {built}"),
-                Dist::Source(source) => format!("Failed to download and build: {source}"),
-            })?;
+        // Fetch the metadata for the distribution.
+        let requires_dist = {
+            // If the metadata is already in the index, return it.
+            if let Some(metadata) = self.index.get_metadata(&dist.package_id()) {
+                metadata.requires_dist.clone()
+            } else {
+                // Run the PEP 517 build process to extract metadata from the source distribution.
+                let (metadata, precise) = self
+                    .database
+                    .get_or_build_wheel_metadata(&dist)
+                    .await
+                    .with_context(|| match &dist {
+                        Dist::Built(built) => format!("Failed to download: {built}"),
+                        Dist::Source(source) => format!("Failed to download and build: {source}"),
+                    })?;
+
+                // Insert the metadata into the index.
+                self.index
+                    .insert_metadata(dist.package_id(), metadata.clone());
+
+                // Insert the redirect into the index.
+                if let Some(precise) = precise {
+                    self.index.insert_redirect(CanonicalUrl::new(url), precise);
+                }
+
+                metadata.requires_dist
+            }
+        };
 
         // Consider the dependencies to be "direct" if the requirement is a local source tree.
         let direct = if let Dist::Source(source_dist) = &dist {
@@ -146,7 +171,7 @@ impl<'a, Context: BuildContext + Send + Sync> LookaheadResolver<'a, Context> {
         // Return the requirements from the metadata.
         Ok(Some(RequestedRequirements::new(
             requirement.extras,
-            metadata.requires_dist,
+            requires_dist,
             direct,
         )))
     }
diff --git a/crates/uv-resolver/src/resolver/index.rs b/crates/uv-resolver/src/resolver/index.rs
index 64692032a..b4eb62132 100644
--- a/crates/uv-resolver/src/resolver/index.rs
+++ b/crates/uv-resolver/src/resolver/index.rs
@@ -1,5 +1,6 @@
 use cache_key::CanonicalUrl;
 use dashmap::DashMap;
+use std::sync::Arc;
 use url::Url;
 
 use distribution_types::PackageId;
@@ -24,3 +25,30 @@ pub struct InMemoryIndex {
     /// `git+https://github.com/pallets/flask.git@c2f65dd1cfff0672b902fd5b30815f0b4137214c`.
     pub(crate) redirects: DashMap<CanonicalUrl, Url>,
 }
+
+impl InMemoryIndex {
+    /// Insert a [`VersionsResponse`] into the index.
+    pub fn insert_package(&self, package_name: PackageName, metadata: VersionsResponse) {
+        self.packages.done(package_name, metadata);
+    }
+
+    /// Insert a [`Metadata23`] into the index.
+    pub fn insert_metadata(&self, package_id: PackageId, metadata: Metadata23) {
+        self.distributions.done(package_id, metadata);
+    }
+
+    /// Insert a redirect from a source URL to a target URL.
+    pub fn insert_redirect(&self, source: CanonicalUrl, target: Url) {
+        self.redirects.insert(source, target);
+    }
+
+    /// Get the [`VersionsResponse`] for a given package name, without waiting.
+    pub fn get_package(&self, package_name: &PackageName) -> Option<Arc<VersionsResponse>> {
+        self.packages.get(package_name)
+    }
+
+    /// Get the [`Metadata23`] for a given package ID, without waiting.
+    pub fn get_metadata(&self, package_id: &PackageId) -> Option<Arc<Metadata23>> {
+        self.distributions.get(package_id)
+    }
+}
diff --git a/crates/uv/src/commands/pip_compile.rs b/crates/uv/src/commands/pip_compile.rs
index 03400c80f..4c2b793c5 100644
--- a/crates/uv/src/commands/pip_compile.rs
+++ b/crates/uv/src/commands/pip_compile.rs
@@ -345,6 +345,7 @@ pub(crate) async fn pip_compile(
         &editables,
         &build_dispatch,
         &client,
+        &top_level_index,
     )
     .with_reporter(ResolverReporter::from(printer))
     .resolve(&markers)
diff --git a/crates/uv/src/commands/pip_install.rs b/crates/uv/src/commands/pip_install.rs
index 93a800f39..3479a3bc0 100644
--- a/crates/uv/src/commands/pip_install.rs
+++ b/crates/uv/src/commands/pip_install.rs
@@ -546,6 +546,7 @@ async fn resolve(
         &editables,
         build_dispatch,
         client,
+        index,
     )
     .with_reporter(ResolverReporter::from(printer))
     .resolve(markers)
diff --git a/crates/uv/tests/pip_compile.rs b/crates/uv/tests/pip_compile.rs
index cce82df56..eb31bf0fd 100644
--- a/crates/uv/tests/pip_compile.rs
+++ b/crates/uv/tests/pip_compile.rs
@@ -1584,8 +1584,8 @@ fn conflicting_transitive_url_dependency() -> Result<()> {
 
     ----- stderr -----
       × No solution found when resolving dependencies:
-      ╰─▶ Because flask==3.0.0 depends on werkzeug>=3.0.0 and only werkzeug<3.0.0
-          is available, we can conclude that flask==3.0.0 cannot be used.
+      ╰─▶ Because only werkzeug<3.0.0 is available and flask==3.0.0 depends on
+          werkzeug>=3.0.0, we can conclude that flask==3.0.0 cannot be used.
           And because you require flask==3.0.0, we can conclude that the
           requirements are unsatisfiable.
     "###